Major depressive disorder is a highly debilitating psychiatric disorder involving the
dysfunction of different cell types in the brain. Microglia are the predominant resident …

Although recent years have seen large decreases in the overall global rate of suicide
fatalities, this trend is not reflected everywhere. Suicide and suicidal behaviour continue to …

Alzheimer disease (AD) is a frequent and devastating neurodegenerative disease in
humans, but still no curative treatment has been developed. Although many explicative …

Psychedelics have inspired new hope for treating brain disorders, as they seem to be unlike
any treatments currently available. Not only do they produce sustained therapeutic effects …

Depression is a major health problem with a high prevalence and a heavy socioeconomic
burden in western societies. It is associated with atrophy and impaired functioning of cortico …

Increasing data indicate that inflammation and alterations in glutamate neurotransmission
are two novel pathways to pathophysiology in mood disorders. The primary goal of this …

Depression is an episodic form of mental illness characterized by mood state transitions with
poorly understood neurobiological mechanisms. Antidepressants reverse the effects of …

Major depressive disorder (MDD) will affect one out of every five people in their lifetime and
is the leading cause of disability worldwide. Nevertheless, mechanisms associated with the …

La depresión mayor representa un problema de salud pública debido a su alta prevalencia.
La etiología de la depresión es compleja ya que en ella intervienen factores psicosociales …

Depression, a severe psychiatric disorder, has been studied for decades, but the underlying
mechanisms still remain largely unknown. Depression is closely associated with alterations …