[HTML][HTML] More treatment but no less depression: The treatment-prevalence paradox
Treatments for depression have improved, and their availability has markedly increased
since the 1980s. Mysteriously the general population prevalence of depression has not …
since the 1980s. Mysteriously the general population prevalence of depression has not …
Tapering of SSRI treatment to mitigate withdrawal symptoms
MA Horowitz, D Taylor - The Lancet Psychiatry, 2019 - thelancet.com
All classes of drug that are prescribed to treat depression are associated with withdrawal
syndromes. SSRI withdrawal syndrome occurs often and can be severe, and might compel …
syndromes. SSRI withdrawal syndrome occurs often and can be severe, and might compel …
Sequential combination of pharmacotherapy and psychotherapy in major depressive disorder: a systematic review and meta-analysis
J Guidi, GA Fava - JAMA psychiatry, 2021 - jamanetwork.com
Importance The sequential model emerged from the awareness that the persistence of
residual symptoms and the frequent occurrence of psychiatric comorbidity were both …
residual symptoms and the frequent occurrence of psychiatric comorbidity were both …
A method for tapering antipsychotic treatment that may minimize the risk of relapse
The process of stopping antipsychotics may be causally related to relapse, potentially linked
to neuroadaptations that persist after cessation, including dopaminergic hypersensitivity …
to neuroadaptations that persist after cessation, including dopaminergic hypersensitivity …
The pursuit of euthymia
GA Fava, J Guidi - World Psychiatry, 2020 - Wiley Online Library
Psychiatrists often consider the positive characteristics displayed by a patient in their clinical
judgment, yet current assessment and treatment strategies are shifted on the side of …
judgment, yet current assessment and treatment strategies are shifted on the side of …
The international prevalence of antidepressant use before, during, and after pregnancy: A systematic review and meta-analysis of timing, type of prescriptions and …
NM Molenaar, B Bais… - Journal of affective …, 2020 - Elsevier
Background Antidepressant use during pregnancy has increased over the last decades,
while safety has been under debate. Our aim was to measure the international prevalence of …
while safety has been under debate. Our aim was to measure the international prevalence of …
Continuation of antidepressants vs sequential psychological interventions to prevent relapse in depression: an individual participant data meta-analysis
Importance Depression frequently recurs. To prevent relapse, antidepressant medication is
often taken in the long term. Sequentially delivering a psychological intervention while …
often taken in the long term. Sequentially delivering a psychological intervention while …
Depression: more treatment but no drop in prevalence: how effective is treatment? And can we do better?
To reduce prevalence, it is essential to narrow the treatment gaps, provide timely
interventions and high-quality treatment, eradicate waiting lists, prescribe antidepressants …
interventions and high-quality treatment, eradicate waiting lists, prescribe antidepressants …
Approaches for discontinuation versus continuation of long‐term antidepressant use for depressive and anxiety disorders in adults
E Van Leeuwen, ML van Driel… - Cochrane Database …, 2021 - cochranelibrary.com
Background Depression and anxiety are the most frequent indication for which
antidepressants are prescribed. Long‐term antidepressant use is driving much of the …
antidepressants are prescribed. Long‐term antidepressant use is driving much of the …
Blinding in randomised clinical trials of psychological interventions: a retrospective study of published trial reports
Objectives To study the extent of blinding in randomised clinical trials of psychological
interventions and the interpretative considerations if randomised clinical trials are not …
interventions and the interpretative considerations if randomised clinical trials are not …