Restorative cell-based and pharmacological therapies for experimental stroke substantially
improve functional outcome. These therapies target several types of parenchymal cells …

Transplantation of bone marrow-derived mesenchymal stromal cells (MSCs) into the injured
brain or spinal cord may provide therapeutic benefit. Several models of central nervous …

Background and Purpose—In animal models of stroke, functional improvement has been
obtained after stem cell transplantation. Successful therapy depends largely on achieving a …

No treatment currently exists to restore lost neurological function after stroke. A growing
number of studies highlight the potential of stem cell transplantation as a novel therapeutic …

Background and Purpose—Intravenously delivered human umbilical cord blood cells
(HUCBC) have been previously shown to improve functional recovery of stroked rats. To …

Transplantation of neural stem cells into the brain is a novel approach to the treatment of
chronic stroke disability. For clinical application, safety and efficacy of defined, stable cell …

Cell therapies are increasingly recognized as a promising option to augment the limited
therapeutic arsenal available to fight ischemic stroke. During the last two decades …

Background and Purpose—Endothelial progenitor cells (EPCs) migrate from bone marrow
to systemic circulation in response to tissue ischemia where they differentiate into mature …

No effective therapy is currently available to promote recovery following ischemic stroke.
Stem cells have been proposed as a potential source of new cells to replace those lost due …

Background: Because granulocyte colony-stimulating factor (G-CSF) has anti-inflammatory
and neuroprotective properties and is known to mobilize stem cells, it may be useful in the …