Protein tyrosine kinases (PTKs) are a class of proteins with tyrosine kinase activity that
phosphorylate tyrosine residues of critical molecules in signaling pathways. Their basal …

Mesenchymal gastrointestinal cancers are represented by the gastrointestinal stromal
tumors (GISTs) which occur throughout the whole gastrointestinal tract, and affect human …

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the
gastrointestinal tract. The majority are sporadic, solitary tumors that harbor mutually …

Gastrointestinal stromal tumor (GIST) is the most common sarcoma located in
gastrointestinal tract and derived from the interstitial cell of Cajal (ICC) lineage. Both ICC …

Gastric cancer (GC) is a major cause of cancer-related mortality worldwide. GC is
determined by multiple (epi) genetic and environmental factors; can occur at distinct …

Simple Summary c-KIT has been regarded as a promising therapeutic target against
gastrointestinal stromal tumor (GIST). Overcoming drug resistance of c-KIT inhibitors …

The HMC-1.2 human mast cell (huMC) line is often employed in the study of attributes of
neoplastic huMCs as found in patients with mastocytosis and their sensitivity to …

Gastrointestinal stromal tumors (GISTs) have been rarely reported in guinea pigs. We aimed
to characterize the clinical and pathological features of GISTs in 4 guinea pigs and …

Several studies have reported the coexistence of gastric gastrointestinal stromal tumors
(GISTs) with many primary carcinomas such as gastric and renal cell carcinomas. However …

Mesenchymal gastrointestinal cancers are represented by the gastrointestinal stromal
tumors (GISTs) which occur throughout the whole gastrointestinal tract, and affect human …