New era of artificial intelligence and machine learning-based detection, diagnosis, and therapeutics in Parkinson's disease

R Gupta, S Kumari, A Senapati, RK Ambasta… - Ageing research …, 2023 - Elsevier
Parkinson's disease (PD) is characterized by the loss of neuronal cells, which leads to
synaptic dysfunction and cognitive defects. Despite the advancements in treatment …

Machine learning within the Parkinson's progression markers initiative: Review of the current state of affairs

RT Gerraty, A Provost, L Li, E Wagner… - Frontiers in Aging …, 2023 - frontiersin.org
The Parkinson's Progression Markers Initiative (PPMI) has collected more than a decade's
worth of longitudinal and multi-modal data from patients, healthy controls, and at-risk …

Blood transcriptomic signatures associated with molecular changes in the brain and clinical outcomes in Parkinson's disease

K Irmady, CR Hale, R Qadri, J Fak, S Simelane… - Nature …, 2023 - nature.com
The ability to use blood to predict the outcomes of Parkinson's disease, including disease
progression and cognitive and motor complications, would be of significant clinical value …

Machine learning analysis of RNA-seq data for diagnostic and prognostic prediction of colon cancer

E Bostanci, E Kocak, M Unal, MS Guzel, K Acici… - Sensors, 2023 - mdpi.com
Data from omics studies have been used for prediction and classification of various diseases
in biomedical and bioinformatics research. In recent years, Machine Learning (ML) …

Artificial Intelligence in Parkinson's Disease: Early Detection and Diagnostic Advancements

A Reddy, RP Reddy, AK Roghani, RI Garcia… - Ageing Research …, 2024 - Elsevier
Parkinson's disease (PD) is the second most common neurodegenerative disorder, globally
affecting men and women at an exponentially growing rate, with currently no cure. Disease …

Alterations in Blood Methylome as Potential Epigenetic Biomarker in Sporadic Parkinson's Disease

P Gonzalez‐Latapi, B Bustos, S Dong… - Annals of …, 2024 - Wiley Online Library
Objective To characterize DNA methylation (DNAm) differences between sporadic
Parkinson's disease (PD) and healthy control (HC) individuals enrolled in the Parkinson's …

Federated learning for multi-omics: A performance evaluation in Parkinson's disease

BP Danek, MB Makarious, A Dadu, D Vitale, PS Lee… - Patterns, 2024 - cell.com
While machine learning (ML) research has recently grown more in popularity, its application
in the omics domain is constrained by access to sufficiently large, high-quality datasets …

A Systematic Review of Genetics-and Molecular-Pathway-Based Machine Learning Models for Neurological Disorder Diagnosis

NA Aljarallah, AK Dutta, ARW Sait - International Journal of Molecular …, 2024 - mdpi.com
The process of identification and management of neurological disorder conditions faces
challenges, prompting the investigation of novel methods in order to improve diagnostic …

DNA methylation changes in autologous hematopoietic stem cell transplant patients

L Mohanraj, H Wolf, S Silvey, J Liu… - Biological Research …, 2023 - journals.sagepub.com
Background Blood cancers may be potentially cured with hematopoietic stem cell
transplantation (HCT); however, standard pre-assessments for transplant eligibility do not …

Machine learning and deep learning approach to Parkinson's disease detection: present state-of-the-art and a bibliometric review

G Sabherwal, A Kaur - Multimedia Tools and Applications, 2024 - Springer
Parkinson's disease (PD) is fatal, severe and irreversible neurological disorder. With the
aging of the world population, the prevalence of PD is on the rise, making it the second most …