Rational design of polymeric micelles for targeted therapeutic delivery

Y Zheng, Y Oz, Y Gu, N Ahamad, K Shariati… - Nano Today, 2024 - Elsevier
Polymeric micellar drug carriers have emerged as effective tools to enhance the solubility
and bioavailability of hydrophobic drugs. These micelles possess a nano size structure that …

Bio-inspired nanomaterials for micro/nanodevices: a new era in biomedical applications

M Harun-Ur-Rashid, I Jahan, T Foyez, AB Imran - Micromachines, 2023 - mdpi.com
Exploring bio-inspired nanomaterials (BINMs) and incorporating them into
micro/nanodevices represent a significant development in biomedical applications …

A panoramic perspective of recent progress in 2D and 3D covalent organic frameworks for drug delivery: Special Issue: Emerging Investigators

F Mehvari, V Ramezanzade, P Asadi, N Singh… - …, 2024 - Wiley Online Library
The development of efficient drug delivery systems is essential for improving the efficacy and
safety of cancer drugs, particularly for aggressive and difficult‐to‐treat cancers. Covalent …

Copolymeric micelles of poly (ε-caprolactone) and poly (methacrylic acid) as carriers for the oral delivery of resveratrol

K Kamenova, L Radeva, S Konstantinov, PD Petrov… - Polymers, 2023 - mdpi.com
In this study, we report the development of a micellar system based on a poly (methacrylic
acid)-b-poly (ε-caprolactone)-b-poly (methacrylic acid) triblock copolymer (PMAA16-b …

Natural Compounds in Non-Melanoma Skin Cancer: Prevention and Treatment

S Kowalski, J Karska, M Tota, K Skinderowicz… - Molecules, 2024 - mdpi.com
The elevated occurrence of non-melanoma skin cancer (NMSC) and the adverse effects
associated with available treatments adversely impact the quality of life in multiple …

[HTML][HTML] How to manage Helicobacter pylori infection beyond antibiotics: The bioengineering quest

DR Fonseca, R Chitas, P Parreira, MCL Martins - Applied Materials Today, 2024 - Elsevier
The rise in antibiotic resistance rate challenges the effective treatment of various bacterial
infections. One of them is the gastric infection caused by Helicobacter pylori, a Gram …

Synthetic Cells Revisited: Artificial Cells Construction Using Polymeric Building Blocks

V Maffeis, L Heuberger, A Nikoletić… - Advanced …, 2024 - Wiley Online Library
The exponential growth of research on artificial cells and organelles underscores their
potential as tools to advance the understanding of fundamental biological processes. The …

Biomaterial-based responsive nanomedicines for targeting solid tumor microenvironments

K Avgoustakis, A Angelopoulou - Pharmaceutics, 2024 - mdpi.com
Solid tumors are composed of a highly complex and heterogenic microenvironment, with
increasing metabolic status. This environment plays a crucial role in the clinical therapeutic …

A pH-responsive cetuximab-conjugated DMAKO-20 nano-delivery system for overcoming K-ras mutations and drug resistance in colorectal carcinoma

H Song, H Li, X Shen, K Liu, H Feng, J Cui, W Wei… - Acta Biomaterialia, 2024 - Elsevier
Cetuximab (Cet) and oxaliplatin (OXA) are used as first-line drugs for patients with colorectal
carcinoma (CRC). In fact, the heterogeneity of CRC, mainly caused by K-ras mutations and …

Multifactorial drug carrier system bringing both chemical and physical therapeutics to the treatment of tumor heterogeneity

EJ Nam, I Cho, H Park, SR Paik - Journal of Controlled Release, 2024 - Elsevier
Tumor heterogeneity and drug resistance have been invincible features of cancer for its
complete cure. Despite the advent of immunotherapy, the expansion and diversification of …