Association between completed suicide and bipolar disorder: A systematic review of the literature

L Plans, C Barrot, E Nieto, J Rios, TG Schulze… - Journal of affective …, 2019 - Elsevier
Background Completed suicide is a major cause of death in bipolar disorder (BD) patients.
Objective The aim of this paper is to provide an overall review of the existing literature of …

Modeling suicide in bipolar disorders

GS Malhi, T Outhred, P Das, G Morris… - Bipolar …, 2018 - Wiley Online Library
Introduction Suicide is a multicausal human behavior, with devastating and immensely
distressing consequences. Its prevalence is estimated to be 20–30 times greater in patients …

Exploring the association between BDNF Val66Met polymorphism and suicidal behavior: meta-analysis and systematic review

TB González-Castro, M Salas-Magaña… - Journal of Psychiatric …, 2017 - Elsevier
Suicide is a serious worldwide health problem of critical consequences. Nowadays genetic
factors are considered to be an important cause of suicide. The association between …

[HTML][HTML] Regulation of miRNA expression in the prefrontal cortex by fecal microbiota transplantation in anxiety-like mice

S Chen, M Li, C Tong, Y Wang, J He, Q Shao… - Frontiers in …, 2024 - frontiersin.org
Background The gut-brain axis and gut microbiota have emerged as key players in
emotional disorders. Recent studies suggest that alterations in gut microbiota may impact …

Multiple sclerosis in men: management considerations

R Bove, A McHenry, K Hellwig, M Houtchens… - Journal of …, 2016 - Springer
Multiple sclerosis (MS) is a lifelong disease typically affecting individuals in young to middle
adulthood. There are recognized sex differences in MS onset and clinical course. MS affects …

Test of a clinical model of poor physical health and suicide: The role of depression, psychosocial stress, interpersonal conflict, and panic

J Black, MA Bond, R Hawkins, E Black - Journal of affective disorders, 2019 - Elsevier
Background This study employed a structural equation model to examine the relationships
between poor physical health, suicide, depression, psychosocial stress, interpersonal …

Initiation and long‐term use of benzodiazepines and Z‐drugs in bipolar disorder

L Wingård, H Taipale, J Reutfors… - Bipolar …, 2018 - Wiley Online Library
Objectives Increasing evidence points to the harmful effects of long‐term benzodiazepine
treatment. Our objective was to study the incidence of, and predictors for, long‐term use of …

Deletion of asparagine endopeptidase reduces anxiety-and depressive-like behaviors and improves abilities of spatial cognition in mice

J Gao, K Li, L Du, H Yin, X Tan, Z Yang - Brain research bulletin, 2018 - Elsevier
Mammalian asparagine endopeptidase (AEP) is a lysosomal cysteine protease that cleaves
protein substrates on the C-terminal side of asparagine. The expression and activity of AEP …

The role of COMT gene Val108/158Met polymorphism in suicidal behavior: systematic review and updated meta-analysis

TB González-Castro, Y Hernández-Díaz… - Neuropsychiatric …, 2018 - Taylor & Francis
Background It is accepted that there is a genetic factor that influences the risk of suicidal
behavior. The catechol-O-methyltransferase (COMT) gene, especially the Val108/158Met …

Association of MIF and MBL2 gene polymorphisms with attempted suicide in patients diagnosed with schizophrenia or bipolar disorder

HM Aytac, Y Oyaci, MS Yazar, A Erol… - Journal of clinical …, 2020 - Elsevier
The aim of this study to investigate the genetic polymorphisms in macrophage inhibitory
factor (MIF) and mannose-binding lectin 2 (MBL2) gene in schizophrenia (SCZ) or bipolar …