Synthesis of 3, 4-dihydropyrimidin (thio) one containing scaffold: Biginelli-like reactions

F Sánchez-Sancho, M Escolano, D Gaviña, AG Csáky… - Pharmaceuticals, 2022 - mdpi.com
The interest in 3, 4-dihydropyrimidine-2 (1 H)-(thio) ones is increasing every day, mainly due
to their paramount biological relevance. The Biginelli reaction is the classical approach to …

Rapid synthesis of fully substituted arylideneisoxazol-5(4H)-one using zinc oxide nanoparticles

S Aslanpour, H Kiyani - Research on Chemical Intermediates, 2023 - Springer
A straightforward, rapid, green, and efficient synthetic procedure has been introduced for
easy access to the synthetically highly substituted arylideneisoxazol-5-(4 H)-one products. A …

Arylideneisoxazole-5(4H)-One Synthesis by Organocatalytic Three-Component Hetero-Cyclization

Z Daroughehzadeh, H Kiyani - Polycyclic Aromatic Compounds, 2024 - Taylor & Francis
An expedient, green, practical, and vastly efficient three-component cyclo-condensation is
catalyzed by triphenylphosphine. The 4-arylideneisoxazol-5 (4 H)-one heterocycles are …

Steglich's base catalyzed three-component synthesis of isoxazol-5-ones

Z Faramarzi, H Kiyani - Polycyclic Aromatic Compounds, 2023 - Taylor & Francis
(Dimethylamino) pyridine (DMAP) has been used as an efficient Brønsted organo-base
catalyst for the one-pot, three-component cyclization of various aldehydes, β-keto esters …

Urea-catalyzed multicomponent synthesis of 4-arylideneisoxazol-5(4H)-one derivatives under green conditions

F Haydari, H Kiyani - Research on Chemical Intermediates, 2023 - Springer
A simple and green one-pot, three-component procedure was used for the efficient synthesis
of different isoxazol-5 (4 H)-ones from aryl/heteroaryl aldehydes, hydroxylamine …

Efficient synthesis of 4-Arylmethylene-3-methylisoxazol-5 (4H)-one derivatives catalyzed by malic acid

SZ Tahmasabi, H Kiyani… - Letters in Organic …, 2023 - ingentaconnect.com
The efficient, straightforward, and green procedure was established in the direction of
synthesis of 4-arylmethylene-3-methylisoxazol-5 (4H)-one derivatives using the malic acid …

Synthesis of Isoxazole-5(4H)-ones Using Citrazinic Acid as an Organocatalyst in Aqueous Conditions

H Ostadzadeh, H Kiyani - Organic Preparations and Procedures …, 2023 - Taylor & Francis
The isoxazolone framework has been found to have a wide variety of biological properties
including, antioxidant, 1 antifungal, 2 antibacterial, 3 fungicide, 4 analgesic, 5 antimicrobial …

An expeditious synthesis of ethyl-2-(4-(arylmethylene)-5-oxo-4, 5-dihydroisoxazol-3-yl) acetate derivatives

AM Delfani, H Kiyani, M Zamani - Current Organic Chemistry, 2022 - ingentaconnect.com
In this contribution, an operationally simple and efficient synthetic procedure for synthesizing
derivatives of 4-(arylmethylene)-5-oxo-4, 5-dihydroisoxazol-3-yl) acetate has been …

Facile synthesis, crystal structure, Hirshfeld surface analysis, DFT calculations, IR and UV–visible spectra analyzes, ADMET and molecular docking studies of …

C Boureghda, A Krid, MA Dems, M Boutebdja… - Journal of Molecular …, 2024 - Elsevier
Isoxazolone derivatives exhibit numerous biological and pharmacological activities. The
search of new procedures for the synthesis of this class of heterocycles is still relevant. Thus …

Chickpea leaf exudates (CLE) mediated Knoevenagel–Michael reactions for the synthesis of diketodiols and biscoumarins

RC Patil, DN Zambare, SA Damate, AA Jagdale… - Research on Chemical …, 2022 - Springer
A green, highly efficient, and eco-friendly protocol for Knoevenagel–Michael addition
reaction is reported in Chickpea leaf exudates (CLE) as a naturally sourced biosurfactant …