Many cellular functions are regulated by calcium (Ca2+) signals that are generated by
different signaling pathways. One of these is the inositol 1, 4, 5-trisphosphate/calcium …

Ionized calcium (Ca2+) is the most versatile cellular messenger. All cells use Ca2+ signals
to regulate their activities in response to extrinsic and intrinsic stimuli. Alterations in cellular …

A wide range of Ca2+ signalling systems deliver the spatial and temporal Ca2+ signals
necessary to control the specific functions of different cell types. Release of Ca2+ by Ins P 3 …

Vitamin D deficiency has been linked to many human diseases such as Alzheimer's disease
(AD), Parkinson's disease (PD), multiple sclerosis (MS), hypertension and cardiovascular …

Calcium (Ca2+) is a critical regulator of cardiac myocyte function. Principally, Ca2+ is the
link between the electrical signals that pervade the heart and contraction of the myocytes to …

Vitamin D is a hormone that maintains healthy cells. It functions by regulating the low resting
levels of cell signalling components such as Ca2+ and reactive oxygen species (ROS). Its …

Rhythmic increases in intracellular Ca2+ concentration underlie the contractile function of
the heart. These heart muscle-wide changes in intracellular Ca2+ are induced and …

Rationale: Inositol 1, 4, 5-trisphosphate (IP3) is a second messenger that regulates
intracellular Ca2+ release through IP3 receptors located in the sarco (endo) plasmic …

CRT partially restores DHF-induced electrophysiological remodeling, abnormal Ca
homeostasis, blunted β-adrenergic responsiveness, and regional heterogeneity of APD, and …

Background—Junctophilin-2 (JPH2), a protein expressed in the junctional membrane
complex, is necessary for proper intracellular calcium (Ca2+) signaling in cardiac myocytes …