The intact blood–milk barrier (BMB) prevents an uncontrolled exchange of soluble and
cellular components between blood and milk in the mammary gland. It enables the …

Epithelial tissues cover most of the external and internal surfaces of the body and its organs.
Inevitably, these tissues serve as first line of defence against inorganic, organic, and …

Epithelia must eliminate apoptotic cells to preserve tissue barriers and prevent inflammation.
1 Several different mechanisms exist for apoptotic clearance, including efferocytosis 2, 3 and …

Extrusion is a mechanism used to eliminate unfit, excess, or dying cells from epithelial
tissues. The initial events guiding which cells will be selectively extruded from the epithelium …

Despite a distinct developmental origin, extraembryonic cells in mice contribute to gut
endoderm and converge to transcriptionally resemble their embryonic counterparts. Notably …

Keratoconus - StatPearls - NCBI Bookshelf US flag An official website of the United States
government Here's how you know NIH NLM Logo Access keys NCBI Homepage MyNCBI …

Epithelia can eliminate apoptotic cells by apical extrusion. This is a complex morphogenetic
event where expulsion of the apoptotic cell is accompanied by rearrangement of its …

Individuals with diabetes have an increased risk of breast, colorectal, pancreatic and
prostate cancer. Metformin, an oral biguanide used to treat diabetes, has anti …

Evasion of cell death is a hallmark of cancer, and consequently the induction of cell death is
a common strategy in cancer treatment. However, the molecular mechanisms regulating …

Blood-gas barrier (BGB) or alveolar-capillary barrier is the primary tissue barrier affected by
coronavirus disease 2019 (COVID-19). Comprising alveolar epithelial cells (AECs) …