Polyphenols are an important family of molecules of vegetal origin present in many
medicinal and edible plants, which represent important alimentary sources in the human …

Stroke is one of the leading causes of death and long-term serious disability. Current
therapeutic strategy is limited to thrombolytic agents, consequently, boosting endogenous …

The aim of this systematic review was to determine whether ethanol is neuroprotective or
associated with adverse effects in the context of traumatic brain injury (TBI). Approximately …

Background and purpose The effect of normobaric oxygen (NBO) on apoptosis remains
controversial. The present study evaluated the effect of NBO on ischemia-induced apoptosis …

Although a known risk factor for traumatic brain injury (TBI), alcohol has been found to both
promote and protect against secondary brain damage. However, it is presently unclear …

Low to moderate alcohol intake has been associated with beneficial effects on the heart and
the vasculature, including improvements in several established and emerging …

Traumatic brain injury (TBI), caused by mechanical impact to the brain, is a leading cause of
death and disability among young adults, with slow and often incomplete recovery …

Pyruvate dehydrogenase (PDH) complex is a mitochondrial matrix enzyme that serves a
critical role in the conversion of anaerobic to aerobic cerebral energy. The regulatory …

Background The surplus cytokines remaining after use in the early stages of the
inflammatory response stimulate immune cells even after the response is over, causing a …

The disruption of cerebral energy metabolism in relation to brain damage has been the
subject of extensive research. However, the pyruvate dehydrogenase complex (PDHC) …