Food flavonols: Nutraceuticals with complex health benefits and functionalities

D Barreca, D Trombetta, A Smeriglio… - Trends in Food Science …, 2021 - Elsevier
Background Flavonols are one of the most promising class of bioactive compounds
belonging to the broad family of the flavonoids, characterized by a unique set of features in …

Therapeutic potential of flavonoids in pain and inflammation: mechanisms of action, pre-clinical and clinical data, and pharmaceutical development

CR Ferraz, TT Carvalho, MF Manchope, NA Artero… - Molecules, 2020 - mdpi.com
Pathological pain can be initiated after inflammation and/or peripheral nerve injury. It is a
consequence of the pathological functioning of the nervous system rather than only a …

Potential clinical benefits of quercetin in the early stage of COVID-19: results of a second, pilot, randomized, controlled and open-label clinical trial

F Di Pierro, S Iqtadar, A Khan… - … journal of general …, 2021 - Taylor & Francis
Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the
cause of the ongoing global pandemic known as COVID-19. Based on the potential antiviral …

Oral co-supplementation of curcumin, quercetin, and vitamin D3 as an adjuvant therapy for mild to moderate symptoms of COVID-19—Results from a pilot open-label …

A Khan, S Iqtadar, SU Mumtaz, M Heinrich… - Frontiers in …, 2022 - frontiersin.org
Background: Curcumin, quercetin, and vitamin D3 (cholecalciferol) are common natural
ingredients of human nutrition and reportedly exhibit promising anti-inflammatory …

An overview and update on the epidemiology of flavonoid intake and cardiovascular disease risk

BH Parmenter, KD Croft, JM Hodgson, F Dalgaard… - Food & function, 2020 - pubs.rsc.org
There is an accumulating body of literature reporting on dietary flavonoid intake and the risk
of cardiovascular disease (CVD) in prospective cohort studies. This makes apparent the …

Quercetin as a therapeutic product: evaluation of its pharmacological action and clinical applications—a review

MA Mirza, S Mahmood, AR Hilles, A Ali, MZ Khan… - Pharmaceuticals, 2023 - mdpi.com
Quercetin is the major polyphenolic flavonoid that belongs to the class called flavanols. It is
found in many foods, such as green tea, cranberry, apple, onions, asparagus, radish leaves …

Clinical advances in immunonutrition and atherosclerosis: a review

AM Ruiz-León, M Lapuente, R Estruch… - Frontiers in …, 2019 - frontiersin.org
Atherosclerosis is a chronic low-grade inflammatory disease that affects large and medium-
sized arteries and is considered to be a major underlying cause of cardiovascular disease …

Randomised clinical trial to determine the safety of quercetin supplementation in patients with chronic obstructive pulmonary disease

MK Han, TA Barreto, FJ Martinez… - BMJ Open …, 2020 - bmjopenrespres.bmj.com
Introduction Quercetin is a plant flavonoid and has potent antioxidant and anti-inflammatory
properties. In a preclinical model of chronic obstructive pulmonary disease (COPD) …

[HTML][HTML] Flavonols and dihydroflavonols inhibit the main protease activity of SARS-CoV-2 and the replication of human coronavirus 229E

Y Zhu, F Scholle, SC Kisthardt, DY Xie - Virology, 2022 - Elsevier
Since December 2019, the deadly novel severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) has caused the current COVID-19 pandemic. To date, vaccines are available …

The effects of quercetin supplementation on lipid profiles and inflammatory markers among patients with metabolic syndrome and related disorders: A systematic …

R Tabrizi, OR Tamtaji, N Mirhosseini… - Critical reviews in …, 2020 - Taylor & Francis
Aims: This systematic review and meta-analysis of randomized controlled trials (RCTs) was
performed to determine the effect of quercetin administration on lipid profiles and …