Inadvertent human genomic bycatch and intentional capture raise beneficial applications and ethical concerns with environmental DNA

L Whitmore, M McCauley, JA Farrell… - Nature Ecology & …, 2023 - nature.com
The field of environmental DNA (eDNA) is advancing rapidly, yet human eDNA applications
remain underutilized and underconsidered. Broader adoption of eDNA analysis will produce …

Entwined African and Asian genetic roots of medieval peoples of the Swahili coast

ES Brielle, J Fleisher, S Wynne-Jones, K Sirak… - Nature, 2023 - nature.com
The urban peoples of the Swahili coast traded across eastern Africa and the Indian Ocean
and were among the first practitioners of Islam among sub-Saharan people,. The extent to …

Time-series sewage metagenomics distinguishes seasonal, human-derived and environmental microbial communities potentially allowing source-attributed …

Á Becsei, A Fuschi, S Otani, R Kant, I Weinstein… - Nature …, 2024 - nature.com
Sewage metagenomics has risen to prominence in urban population surveillance of
pathogens and antimicrobial resistance (AMR). Unknown species with similarity to known …

Balancing public health and group privacy: ethics, rights, and obligations for wastewater surveillance systems

D Nainani, WJ Ng, S Wuertz, JR Thompson - Water Research, 2024 - Elsevier
As the threat of COVID-19 recedes, wastewater surveillance–unlike other pandemic-era
public health surveillance methods–seems here to stay. Concerns have been raised …

Wastewater monitoring raises privacy and ethical considerations

D Jacobs, T McDaniel, A Varsani… - … on Technology and …, 2021 - ieeexplore.ieee.org
Analysis of municipal wastewater, or sewage for public health applications is a rapidly
expanding field aimed at understanding emerging epidemiological trends, including human …

The mitochondrial challenge: Disorders and prevention strategies

E Korchivaia, Y Silaeva, I Mazunin, I Volodyaev - Biosystems, 2023 - Elsevier
This short review provides basic knowledge on mitochondrial inheritance, its disorders, and
potential ways to overcome them in human reproductive medicine. The latter are currently …

Comparison of the optimal and suboptimal quantity of mitotype libraries using next-generation sequencing

M Obal, T Zupanc, I Zupanič Pajnič - International journal of legal medicine, 2024 - Springer
Optimizing analysis parameters and sample input is crucial in forensic genetics methods to
generate reliable results, and even more so when working with muti-copy mitochondrial …

Socioeconomic drivers of the human microbiome footprint in global sewage

M Ren, S Du, J Wang - Frontiers of Environmental Science & Engineering, 2024 - Springer
The human microbiome leaves a legacy in sewage ecosystems, also referred to as the
human sewage microbiomes (HSM), and could cause potential risk to human health and …

Global distribution and diversity of prevalent sewage water plasmidomes

F Teudt, S Otani, FM Aarestrup - Msystems, 2022 - Am Soc Microbiol
Sewage water from around the world contains an abundance of short plasmids, several of
which harbor antimicrobial resistance genes (ARGs). The global dynamics of plasmid …

Pilot screening of cell-free mtDNA in NIPT: quality control, variant calling, and Haplogroup determination

A Morshneva, P Kozyulina, E Vashukova, O Tarasenko… - Genes, 2021 - mdpi.com
Clinical tests based on whole-genome sequencing are generally focused on a single task
approach, testing one or several parameters, although whole-genome sequencing (WGS) …