Continuous flow technology-a tool for safer oxidation chemistry
L Wan, M Jiang, D Cheng, M Liu, F Chen - Reaction Chemistry & …, 2022 - pubs.rsc.org
The oxidation reaction is one of the most important transformations in synthetic chemistry,
allowing for the introduction and modification of various functional groups. Continuous flow …
allowing for the introduction and modification of various functional groups. Continuous flow …
Flowmicro In‐Line Analysis‐Driven Design of Reactions Mediated by Unstable Intermediates: Flash Monitoring Approach
Y Ashikari, R Yoshioka, Y Yonekura… - … A European Journal, 2024 - Wiley Online Library
The direct observation of reactive intermediates is an important issue for organic synthesis.
However, intermediates with an extreme instability are hard to be monitored by common …
However, intermediates with an extreme instability are hard to be monitored by common …
Highly Productive Flow Synthesis for Lithiation, Borylation, and/or Suzuki Coupling Reaction
H Soutome, K Maekawa, Y Ashikari… - … Process Research & …, 2024 - ACS Publications
The efficient synthesis of aromatic boronic acids was achieved by increasing the
concentration, flow rate, and mixer diameter to prevent clogging. A 1 h synthesis actually …
concentration, flow rate, and mixer diameter to prevent clogging. A 1 h synthesis actually …
Switchable chemoselectivity of reactive intermediates formation and their direct use in a flow microreactor
Y Ashikari, T Tamaki, T Kawaguchi… - … A European Journal, 2021 - Wiley Online Library
A chemoselectivity switchable microflow reaction was developed to generate reactive and
unstable intermediates. The switchable chemoselectivity of this reaction enables a selection …
unstable intermediates. The switchable chemoselectivity of this reaction enables a selection …
Synthesis of Deuterated Compounds by Flow Chemistry
S Kamio, K Okamoto, T Yamagishi, A Nagaki - ChemPlusChem, 2024 - Wiley Online Library
Abstract Development of the efficient and practical method for the synthesis of deuterated
compounds which occupies the broadest area among stable isotopes is one of the most …
compounds which occupies the broadest area among stable isotopes is one of the most …
Electrocatalytic Reduction of (Hetero) Aryl Halides in a Proton‐Exchange Membrane Reactor and its Application for Deuteration
Y Ashikari, K Mandai, Y Yao, Y Tsuchihashi… - …, 2023 - Wiley Online Library
We developed an electrocatalytic reduction of (hetero) aryl halides under mild conditions
using a proton exchange membrane (PEM) reactor. This approach allows substituting the …
using a proton exchange membrane (PEM) reactor. This approach allows substituting the …
Photochemical hydrothiolation of amorphadiene and formal synthesis of artemisinin via a Pummerer rearrangement
MA Gomez Fernandez, M Nascimento de Oliveira… - Organic …, 2021 - ACS Publications
A new access to artemisinin is reported based on a selective photochemical hydrothiolation
of amorphadiene, a waste product of the industrial semisynthetic route. This study highlights …
of amorphadiene, a waste product of the industrial semisynthetic route. This study highlights …
[HTML][HTML] Stille, Heck, and Sonogashira coupling and hydrogenation catalyzed by porous-silica-gel-supported palladium in batch and flow
Y Ashikari, K Maekawa, M Ishibashi, C Fujita… - Green Processing and …, 2021 - degruyter.com
Owing to their recyclability, heterogeneous transition metal catalysts represent a means of
conserving depletable resources for the synthesis of pharmaceutical, agricultural, and …
conserving depletable resources for the synthesis of pharmaceutical, agricultural, and …
Selective Hydroboration/Oxidation of Alkenes Using 9-BBN under Flow Conditions
Selective Hydroboration/Oxidation of Alkenes Using 9-BBN under Flow Conditions Page 1 ©
2020. Thieme. All rights reserved. Georg Thieme Verlag KG, Rüdigerstraße 14, 70469 Stuttgart …
2020. Thieme. All rights reserved. Georg Thieme Verlag KG, Rüdigerstraße 14, 70469 Stuttgart …