While the processing of mRNA is essential for gene expression, recent findings have
highlighted that RNA processing is systematically altered in cancer. Mutations in RNA …

Colorectal cancer (CRC), a leading cause of cancer-related death worldwide, evolves as a
result of the stepwise accumulation of a series of genetic and epigenetic alterations in the …

Altered gene expression is the primary molecular mechanism responsible for the
pathological processes of human diseases, including cancer. MicroRNAs (miRNAs) are …

Epithelial–mesenchymal plasticity (EMP) enables cells to interconvert between several
states across the epithelial–mesenchymal landscape, thereby acquiring hybrid epithelial …

Epigenetics is dynamic and heritable modifications to the genome that occur independently
of DNA sequence. It requires interactions cohesively with various enzymes and other …

Epithelial-mesenchymal transition (EMT) is described as the process in which injured renal
tubular epithelial cells undergo a phenotype change, acquiring mesenchymal characteristics …

Epithelial to mesenchymal transition (EMT) is a process during which cells lose their
epithelial characteristics, for instance cell polarity and cell–cell contact, and gain …

Simple Summary MicroRNAs (miRNAs) are small RNA molecules that regulate gene
expression by blocking translation or inducing degradation of specific gene transcripts. The …

Mutations of the tricarboxylic acid cycle enzyme fumarate hydratase cause hereditary
leiomyomatosis and renal cell cancer. Fumarate hydratase-deficient renal cancers are …

Epithelial to mesenchymal transition (EMT) is essential for driving plasticity during
development, but is an unintentional behaviour of cells during cancer progression. The EMT …