[HTML][HTML] Potential mechanisms of bisphenol A (BPA) contributing to human disease

I Cimmino, F Fiory, G Perruolo, C Miele… - International journal of …, 2020 - mdpi.com
Bisphenol A (BPA) is an organic synthetic compound serving as a monomer to produce
polycarbonate plastic, widely used in the packaging for food and drinks, medical devices …

Gene regulatory programmes of tissue regeneration

JA Goldman, KD Poss - Nature Reviews Genetics, 2020 - nature.com
Regeneration is the process by which organisms replace lost or damaged tissue, and
regenerative capacity can vary greatly among species, tissues and life stages. Tissue …

Heart regeneration and repair after myocardial infarction: translational opportunities for novel therapeutics

TJ Cahill, RP Choudhury, PR Riley - Nature reviews Drug discovery, 2017 - nature.com
Current therapies for heart failure after myocardial infarction are limited and non-curative.
Although regenerative approaches are receiving significant attention, clinical efforts that …

[PDF][PDF] Mechanisms of cardiac regeneration

A Uygur, RT Lee - Developmental cell, 2016 - cell.com
Adult humans fail to regenerate their hearts following injury, and this failure to regenerate
myocardium is a leading cause of heart failure and death worldwide. Although all adult …

Zebrafish heart regeneration: 15 years of discoveries

JM González‐Rosa, CE Burns, CG Burns - Regeneration, 2017 - Wiley Online Library
Cardiovascular disease is the leading cause of death worldwide. Compared to other organs
such as the liver, the adult human heart lacks the capacity to regenerate on a macroscopic …

Stimulation of glycolysis promotes cardiomyocyte proliferation after injury in adult zebrafish

R Fukuda, R Marín‐Juez, H El‐Sammak, A Beisaw… - EMBO …, 2020 - embopress.org
Cardiac metabolism plays a crucial role in producing sufficient energy to sustain cardiac
function. However, the role of metabolism in different aspects of cardiomyocyte regeneration …

Developmental toxicity of 2, 4-dichlorophenoxyacetic acid in zebrafish embryos

K Li, JQ Wu, LL Jiang, LZ Shen, JY Li, ZH He, P Wei… - Chemosphere, 2017 - Elsevier
Dichlorophenoxyacetic acid (2, 4-D) is widely used in agriculture as herbicide/pesticide,
plant growth regulator and fruit preservative agent. It progressively accumulates in the …

[HTML][HTML] Molecular mechanism of hippo–YAP1/TAZ pathway in heart development, disease, and regeneration

X Chen, Y Li, J Luo, N Hou - Frontiers in physiology, 2020 - frontiersin.org
The Hippo–YAP1/TAZ pathway is a highly conserved central mechanism that controls organ
size through the regulation of cell proliferation and other physical attributes of cells. The …

[PDF][PDF] The lncRNA locus handsdown regulates cardiac gene programs and is essential for early mouse development

N Ritter, T Ali, N Kopitchinski, P Schuster, A Beisaw… - Developmental cell, 2019 - cell.com
Precisely controlled gene regulatory networks are required during embryonic development
to give rise to various structures, including those of the cardiovascular system. Long non …

[HTML][HTML] Evolution, comparative biology and ontogeny of vertebrate heart regeneration

CJ Vivien, JE Hudson, ER Porrello - NPJ Regenerative medicine, 2016 - nature.com
There are 64,000 living species of vertebrates on our planet and all of them have a heart.
Comparative analyses devoted to understanding the regenerative potential of the …