Recent advances in models, mechanisms, biomarkers, and interventions in cisplatin-induced acute kidney injury
SJ Holditch, CN Brown, AM Lombardi… - International journal of …, 2019 - mdpi.com
Cisplatin is a widely used chemotherapeutic agent used to treat solid tumours, such as
ovarian, head and neck, and testicular germ cell. A known complication of cisplatin …
ovarian, head and neck, and testicular germ cell. A known complication of cisplatin …
Molecular mechanisms of cisplatin-induced nephrotoxicity: a balance on the knife edge between renoprotection and tumor toxicity
V Volarevic, B Djokovic, MG Jankovic… - Journal of biomedical …, 2019 - Springer
Background Cisplatin (cis-diamminedichloroplatinum II, CDDP) is one of the most effective
chemotherapeutic agents. However, its clinical use is limited due to the severe side effects …
chemotherapeutic agents. However, its clinical use is limited due to the severe side effects …
Bee venom: an updating review of its bioactive molecules and its health applications
M Carpena, B Nuñez-Estevez, A Soria-Lopez… - Nutrients, 2020 - mdpi.com
Bee venom (BV) is usually associated with pain since, when humans are stung by bees,
local inflammation and even an allergic reaction can be produced. BV has been traditionally …
local inflammation and even an allergic reaction can be produced. BV has been traditionally …
[HTML][HTML] Pharmacological properties and therapeutic potential of honey bee venom
Honey bee venom (BV) is a valuable product, and has a wide range of biological effects,
and its use is rapidly increasing in apitherapy. Therefore, the current study, we reviewed the …
and its use is rapidly increasing in apitherapy. Therefore, the current study, we reviewed the …
Impact of bee venom enzymes on diseases and immune responses
Bee venom (BV) is used to treat many diseases and exhibits anti-inflammatory, anti-
bacterial, antimutagenic, radioprotective, anti-nociceptive immunity promoting, hepatocyte …
bacterial, antimutagenic, radioprotective, anti-nociceptive immunity promoting, hepatocyte …
[HTML][HTML] MiR-155 deficiency protects renal tubular epithelial cells from telomeric and genomic DNA damage in cisplatin-induced acute kidney injury
Q Yin, YJ Zhao, WJ Ni, TT Tang, Y Wang, JY Cao… - Theranostics, 2022 - ncbi.nlm.nih.gov
Rationale: Cisplatin nephrotoxicity is an important cause of acute kidney injury (AKI), limiting
cisplatin application in cancer therapy. Growing evidence has suggested that genome …
cisplatin application in cancer therapy. Growing evidence has suggested that genome …
Bee Venom Phospholipase A2: Yesterday's Enemy Becomes Today's Friend
Bee venom therapy has been used to treat immune-related diseases such as arthritis for a
long time. Recently, it has revealed that group III secretory phospholipase A2 from bee …
long time. Recently, it has revealed that group III secretory phospholipase A2 from bee …
Neuroprotective effects of bee venom phospholipase A2 in the 3xTg AD mouse model of Alzheimer's disease
M Ye, HS Chung, C Lee, MS Yoon, AR Yu… - Journal of …, 2016 - Springer
Background Alzheimer's disease (AD) is a severe neuroinflammatory disease. CD4+
Foxp3+ regulatory T cells (Tregs) modulate various inflammatory diseases via suppressing …
Foxp3+ regulatory T cells (Tregs) modulate various inflammatory diseases via suppressing …
Dexmedetomidine protects against cisplatin-induced acute kidney injury in mice through regulating apoptosis and inflammation
H Liang, HZ Liu, HB Wang, JY Zhong, CX Yang… - Inflammation …, 2017 - Springer
Objective and design Cisplatin-based chemotherapy has been widely used in the
perioperative period of cancer surgery, which exacerbates the risk of renal injury. In this …
perioperative period of cancer surgery, which exacerbates the risk of renal injury. In this …
Regulatory T cells in acute and chronic kidney diseases
Foxp3-expressing CD4+ regulatory T cells (Tregs) make up one subset of the helper T cells
(Th) and are one of the major mechanisms of peripheral tolerance. Tregs prevent abnormal …
(Th) and are one of the major mechanisms of peripheral tolerance. Tregs prevent abnormal …