Lifestyle and metabolic syndrome: contribution of the endocannabinoidome

V Di Marzo, C Silvestri - Nutrients, 2019 - mdpi.com
Lifestyle is a well-known environmental factor that plays a major role in facilitating the
development of metabolic syndrome or eventually exacerbating its consequences. Various …

The selective peroxisome proliferator-activated receptor alpha modulator (SPPARMα) paradigm: conceptual framework and therapeutic potential: a consensus …

JC Fruchart, RD Santos, C Aguilar-Salinas… - Cardiovascular …, 2019 - Springer
In the era of precision medicine, treatments that target specific modifiable characteristics of
high-risk patients have the potential to lower further the residual risk of atherosclerotic …

American Association of Clinical Endocrinology clinical practice guideline: developing a diabetes mellitus comprehensive care plan—2022 update

L Blonde, GE Umpierrez, SS Reddy, JB McGill… - Endocrine Practice, 2022 - Elsevier
Objective The objective of this clinical practice guideline is to provide updated and new
evidence-based recommendations for the comprehensive care of persons with diabetes …

American Association of Clinical Endocrinology Consensus Statement: comprehensive type 2 diabetes management algorithm–2023 update

SL Samson, P Vellanki, L Blonde, EA Christofides… - Endocrine Practice, 2023 - Elsevier
Objective This consensus statement provides (1) visual guidance in concise graphic
algorithms to assist with clinical decision-making of health care professionals in the …

Menopause symptom management in women with dyslipidemias: an EMAS clinical guide

P Anagnostis, J Bitzer, A Cano, I Ceausu, P Chedraui… - Maturitas, 2020 - Elsevier
Introduction Dyslipidemias are common and increase the risk of cardiovascular disease. The
menopause transition is associated with an atherogenic lipid profile, with an increase in the …

Obesity affects the microbiota–gut–brain axis and the regulation thereof by endocannabinoids and related mediators

N Forte, AC Fernández-Rilo, L Palomba… - International Journal of …, 2020 - mdpi.com
The hypothalamus regulates energy homeostasis by integrating environmental and internal
signals to produce behavioral responses to start or stop eating. Many satiation signals are …

Targeting platelet in atherosclerosis plaque formation: current knowledge and future perspectives

L Wang, C Tang - International journal of molecular sciences, 2020 - mdpi.com
Besides their role in hemostasis and thrombosis, it has become increasingly clear that
platelets are also involved in many other pathological processes of the vascular system …

Reducing residual cardiovascular risk in Europe: therapeutic implications of European medicines agency approval of icosapent ethyl/eicosapentaenoic acid

MJ Chapman, JL Zamorano, KG Parhofer - Pharmacology & therapeutics, 2022 - Elsevier
Atherosclerotic cardiovascular disease (ASCVD) and its atherothrombotic complications
impose a substantial disease burden in Europe, representing a cost of€ 210 billion per year …

NAFLD and cardiovascular diseases: epidemiological, mechanistic and therapeutic considerations

D Niederseer, B Wernly, E Aigner, F Stickel… - Journal of Clinical …, 2021 - mdpi.com
Overwhelming evidence suggests an association of cardiovascular disease (CVD) with non-
alcoholic fatty liver disease (NAFLD); however, the underlying mechanisms remain largely …

Profound reductions in first and total cardiovascular events with icosapent ethyl in the REDUCE-IT trial: why these results usher in a new era in dyslipidaemia …

WE Boden, DL Bhatt, PP Toth, KK Ray… - European heart …, 2020 - academic.oup.com
The aims of this clinical review are to:(i) highlight the importance of elevated baseline
triglycerides (TG) in the setting of well-controlled low-density lipoprotein cholesterol (LDL-C) …