Chikungunya virus: an update on the biology and pathogenesis of this emerging pathogen
Re-emergence of chikungunya virus, a mosquito-transmitted pathogen, is of serious public
health concern. In the past 15 years, after decades of infrequent, sporadic outbreaks, the …
health concern. In the past 15 years, after decades of infrequent, sporadic outbreaks, the …
CNS infection and immune privilege
JV Forrester, PG McMenamin, SJ Dando - Nature Reviews …, 2018 - nature.com
Classically, the CNS is described as displaying immune privilege, as it shows attenuated
responses to challenge by alloantigen. However, the CNS does show local inflammation in …
responses to challenge by alloantigen. However, the CNS does show local inflammation in …
[HTML][HTML] Curcumin inhibits Zika and chikungunya virus infection by inhibiting cell binding
Several compounds extracted from spices and herbs exhibit antiviral effects in vitro,
suggesting potential pharmacological uses. Curcumin, a component of turmeric, has been …
suggesting potential pharmacological uses. Curcumin, a component of turmeric, has been …
Chikungunya fever: epidemiology, clinical syndrome, pathogenesis and therapy
SD Thiberville, N Moyen, L Dupuis-Maguiraga… - Antiviral research, 2013 - Elsevier
Chikungunya virus (CHIKV) is the aetiological agent of the mosquito-borne disease
chikungunya fever, a debilitating arthritic disease that, during the past 7 years, has caused …
chikungunya fever, a debilitating arthritic disease that, during the past 7 years, has caused …
Global virus outbreaks: Interferons as 1st responders
BX Wang, EN Fish - Seminars in immunology, 2019 - Elsevier
Outbreaks of severe virus infections with the potential to cause global pandemics are
increasing. In many instances these outbreaks have been newly emerging (SARS …
increasing. In many instances these outbreaks have been newly emerging (SARS …
Arthritogenic alphaviruses—an overview
A Suhrbier, MC Jaffar-Bandjee, P Gasque - Nature Reviews …, 2012 - nature.com
Mosquito-transmitted alphaviruses causing human rheumatic disease are globally
distributed and include chikungunya virus, Ross River virus, Barmah Forest virus, Sindbis …
distributed and include chikungunya virus, Ross River virus, Barmah Forest virus, Sindbis …
Insect antiviral innate immunity: pathways, effectors, and connections
MB Kingsolver, Z Huang, RW Hardy - Journal of molecular biology, 2013 - Elsevier
Insects are infected by a wide array of viruses some of which are insect restricted and
pathogenic, and some of which are transmitted by biting insects to vertebrates. The medical …
pathogenic, and some of which are transmitted by biting insects to vertebrates. The medical …
Noncoding flavivirus RNA displays RNA interference suppressor activity in insect and Mammalian cells
E Schnettler, MG Sterken, JY Leung, SW Metz… - Journal of …, 2012 - Am Soc Microbiol
West Nile virus (WNV) and dengue virus (DENV) are highly pathogenic, mosquito-borne
flaviviruses (family Flaviviridae) that cause severe disease and death in humans. WNV and …
flaviviruses (family Flaviviridae) that cause severe disease and death in humans. WNV and …
Inhibitors of alphavirus entry and replication identified with a stable Chikungunya replicon cell line and virus-based assays
Chikungunya virus (CHIKV), an alphavirus, has recently caused epidemic outbreaks and is
therefore considered a re-emerging pathogen for which no effective treatment is available. In …
therefore considered a re-emerging pathogen for which no effective treatment is available. In …
[HTML][HTML] A mouse model of chikungunya virus–induced musculoskeletal inflammatory disease: evidence of arthritis, tenosynovitis, myositis, and persistence
TE Morrison, L Oko, SA Montgomery… - The American journal of …, 2011 - Elsevier
Chikungunya virus (CHIKV), an emerging mosquito-borne Alphavirus, causes debilitating
rheumatic disease in humans that can last for weeks to months. Starting in 2004, a CHIKV …
rheumatic disease in humans that can last for weeks to months. Starting in 2004, a CHIKV …