MicroRNAs (miRNAs) are a class of small (∼ 22 nucleotides) noncoding RNAs involved in
the regulation of gene expression at the post‐translational level. It is estimated that 30–90 …

Fibroblast growth factor (FGF) signalling has been implicated during several phases of early
embryogenesis, including the patterning of the embryonic axes, the induction and/or …

Influx of macrophages plays a crucial role in tissue repair. However, the precise function of
macrophages during the healing response has remained a subject of debate due to their …

Understanding the molecular mechanisms that promote successful tissue regeneration is
critical for continued advancements in regenerative medicine. Vertebrate amphibian …

Amphibians are among the vertebrate groups suffering great losses of biodiversity due to a
variety of causes including diseases, such as chytridiomycosis (caused by the fungal …

Background The molecular mechanisms governing vertebrate appendage regeneration
remain poorly understood. Uncovering these mechanisms may lead to novel therapies …

Nicotinamide adenine dinucleotide phosphate (NADP) is a critical cofactor during
metabolism, calcium signaling, and oxidative defense, yet how animals regulate their NADP …

Monocyte/macrophages are important players in orchestrating the immune response as well
as connecting innate and adaptive immunity. Myelopoiesis and monopoiesis are …

There remains a critical need for new therapeutics that promote wound healing in patients
suffering from chronic skin wounds. This is, in part, due to a shortage of simple …

Survival of any living organism critically depends on its ability to repair and regenerate
damaged tissues and/or organs during its lifetime following injury, disease, or aging. Various …