Drug conjugates and their use for treating cancer, an autoimmune disease or an infectious disease

PD Senter, SO Doronina, BE Toki - US Patent 7,659,241, 2010 - Google Patents
US7659241B2 - Drug conjugates and their use for treating cancer, an autoimmune disease or
an infectious disease - Google Patents US7659241B2 - Drug conjugates and their use for …

Drug conjugates and their use for treating cancer, an autoimmune disease or an infectious disease

PD Senter, SO Doronina, BE Toki - US Patent 7,829,531, 2010 - Google Patents
0 [2*] N (C (C) C) C ([3*]) C (= O) NC ([4*])([5*]) C (= O) N ([6*]) C ([7*]) C ([8*]) CC (= O)
N1CCCC1C ([8*]) C (C) C (= O) N ([9*])[10*] Chemical compound [2*] N (C (C) C) C ([3*]) C …

Monomethylvaline compounds capable of conjugation to ligands

SO Doronina, PD Senter, BE Toki, AJ Ebens… - US Patent …, 2010 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
34916511&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Antibodies that block receptor protein tyrosine kinase activation, methods of screening for and uses thereof

A Yayon, E Rom, E Thomassen-Wolf… - US Patent …, 2009 - Google Patents
US7498416B2 - Antibodies that block receptor protein tyrosine kinase activation, methods of
screening for and uses thereof - Google Patents US7498416B2 - Antibodies that block …

Humanized anti-CD70 binding agents and uses thereof

C McDonagh, P Carter, J McEarchern… - US Patent 8,067,546, 2011 - Google Patents
2006-10-27 Assigned to SEATTLE GENETICS, INC. reassignment SEATTLE GENETICS,
INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS) …

Anti-IGF-IR antibodies and uses thereof

L Goetsch, N Corvaia, O Leger, A Duflos… - US Patent …, 2007 - Google Patents
The present invention relates to novel antibodies capable of binding specifically to the
human insulin-like growth factor I receptor IGF-IR and/or capable of specifically inhibiting the …

Anti-CD70 antibody-drug conjugates and their use for the treatment of cancer and immune disorders

CL Law, AF Wahl, N Scholler, LA Pestano - US Patent 7,662,387, 2010 - Google Patents
Disclosed are anti-CD70 antibodies and derivatives thereof conjugated to cytotoxic,
immunosuppressive, or other thera peutic agents, as well as pharmaceutical compositions …

Antibody conjugate methods for selectively inhibiting VEGF

PE Thorpe, RA Brekken - US Patent 6,703,020, 2004 - Google Patents
2000-09-05 Assigned to BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
reassignment BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM ASSIGNMENT …

Hydrophilic linkers and their uses for conjugation of drugs to a cell binding molecules

RY Zhao - US Patent 10,131,682, 2018 - Google Patents
US10131682B2 - Hydrophilic linkers and their uses for conjugation of drugs to a cell
binding molecules - Google Patents US10131682B2 - Hydrophilic linkers and their uses for …

Antibodies directed to angiopoietin-2 and uses thereof

LL Green, Q Zhou, BA Keyt, XD Yang… - US Patent …, 2011 - Google Patents
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