Hormonal treatments for endometriosis: The endocrine background

S Vannuccini, S Clemenza, M Rossi… - Reviews in Endocrine and …, 2022 - Springer
Endometriosis is a benign uterine disorder characterized by menstrual pain and infertility,
deeply affecting women's health. It is a chronic disease and requires a long term …

The changing face of Turner syndrome

CH Gravholt, M Viuff, J Just, K Sandahl… - Endocrine …, 2023 - academic.oup.com
Turner syndrome (TS) is a condition in females missing the second sex chromosome (45, X)
or parts thereof. It is considered a rare genetic condition and is associated with a wide range …

Biomarkers in breast cancer: an old story with a new end

L Neves Rebello Alves, D Dummer Meira… - Genes, 2023 - mdpi.com
Breast cancer is the second most frequent cancer in the world. It is a heterogeneous disease
and the leading cause of cancer mortality in women. Advances in molecular technologies …

Progesterone signaling and uterine fibroid pathogenesis; molecular mechanisms and potential therapeutics

M Ali, M Ciebiera, S Vafaei, S Alkhrait, HY Chen… - Cells, 2023 - mdpi.com
Uterine fibroids (UFs) are the most important benign neoplastic threat to women's health
worldwide, with a prevalence of up to 80% in premenopausal women, and can cause heavy …

Isoflavone consumption and risk of breast Cancer: an updated systematic review with Meta-analysis of observational studies

J Yang, H Shen, M Mi, Y Qin - Nutrients, 2023 - mdpi.com
Rationale: Epidemiological studies that focus on the relationship between dietary isoflavone
intake and the risk of breast cancer still lead to inconsistent conclusions. Herein, we …

Diagnosis and management of uterine fibroids: current trends and future strategies

A Ahmad, M Kumar, NR Bhoi, Badruddeen… - Journal of basic and …, 2023 - degruyter.com
Uterine fibroids (UFs), leiomyomas or myomas, are a type of malignancy that affects the
smooth muscle of the uterus, and it is most commonly detected in women of reproductive …

Epigenomic and enhancer dysregulation in uterine leiomyomas

OW Mlodawska, P Saini, JB Parker… - Human …, 2022 - academic.oup.com
BACKGROUND Uterine leiomyomas, also known as uterine fibroids or myomas, are the
most common benign gynecological tumors and are found in women of reproductive and …

Recent Advances in Transcription Factors Biomarkers and Targeted Therapies Focusing on Epithelial–Mesenchymal Transition

KT Chuang, SS Chiou, SH Hsu - Cancers, 2023 - mdpi.com
Simple Summary The study discusses the potential of targeting transcription factors (TFs) for
cancer therapy and provide a systematic classification of various types of TFs involved in the …

Novel pharmacological therapies for the treatment of endometriosis

L Buggio, D Dridi, G Barbara, CEM Merli… - Expert Review of …, 2022 - Taylor & Francis
Introduction Endometriosis is a chronic, estrogen-dependent, inflammatory disease
associated with pelvic pain, infertility, impaired sexual function, and psychological suffering …

Membrane progesterone receptors (mPRs/PAQRs) are going beyond its initial definitions

J Aickareth, M Hawwar, N Sanchez, R Gnanasekaran… - Membranes, 2023 - mdpi.com
Progesterone (PRG) is a key cyclical reproductive hormone that has a significant impact on
female organs in vertebrates. It is mainly produced by the corpus luteum of the ovaries, but …