Screening and testing for endocrine disruption in fish—biomarkers as “signposts,” not “traffic lights,” in risk assessment
Biomarkers are currently best used as mechanistic “signposts” rather than as “traffic lights” in
the environmental risk assessment of endocrine-disrupting chemicals (EDCs). In field …
the environmental risk assessment of endocrine-disrupting chemicals (EDCs). In field …
Predicted‐no‐effect concentrations for the steroid estrogens estrone, 17β‐estradiol, estriol, and 17α‐ethinylestradiol
DJ Caldwell, F Mastrocco, PD Anderson… - Environmental …, 2012 - Wiley Online Library
The authors derive predicted‐no‐effect concentrations (PNECs) for the steroid estrogens
(estrone [E1], 17β‐estradiol [E2], estriol [E3], and 17α‐ethinylestradiol [EE2]) appropriate for …
(estrone [E1], 17β‐estradiol [E2], estriol [E3], and 17α‐ethinylestradiol [EE2]) appropriate for …
Transgenic fish systems and their application in ecotoxicology
The use of transgenics in fish is a relatively recent development for advancing
understanding of genetic mechanisms and developmental processes, improving …
understanding of genetic mechanisms and developmental processes, improving …
Mixtures of estrogenic contaminants in bile of fish exposed to wastewater treatment works effluents
Most effluents from wastewater treatment works (WwTWs) contain estrogenic chemicals that
include steroidal estrogens and xenoestrogens. We investigated the nature of mixtures of …
include steroidal estrogens and xenoestrogens. We investigated the nature of mixtures of …
Using NMR metabolomics to identify responses of an environmental estrogen in blood plasma of fish
LM Samuelsson, L Förlin, G Karlsson… - Aquatic toxicology, 2006 - Elsevier
Nuclear magnetic resonance (NMR) based metabolomics in combination with multivariate
data analysis may become valuable tools to study environmental effects of pharmaceuticals …
data analysis may become valuable tools to study environmental effects of pharmaceuticals …
Pharmaceutical industry effluent diluted 1: 500 affects global gene expression, cytochrome P450 1A activity, and plasma phosphate in fish
L Gunnarsson, E Kristiansson… - Environmental …, 2009 - Wiley Online Library
Abstract Patancheru, near Hyderabad, India, is a major production site for the global bulk
drug market. Approximately 90 manufacturers send their wastewater to a common treatment …
drug market. Approximately 90 manufacturers send their wastewater to a common treatment …
Gonadal transcriptome responses and physiological consequences of exposure to oestrogen in breeding zebrafish (Danio rerio)
Environmental oestrogens are widespread in the aquatic environment and cause alterations
in sexual development and function in vertebrates. The molecular pathways underpinning …
in sexual development and function in vertebrates. The molecular pathways underpinning …
Accounting for Differences in Estrogenic Responses in Rainbow Trout (Oncorhynchus mykiss: Salmonidae) and Roach (Rutilus rutilus: Cyprinidae) Exposed to …
Effluents from wastewater treatment works (WwTWs) contain estrogenic substances that
induce feminizing effects in fish, including vitellogenin (VTG) synthesis and gonadal …
induce feminizing effects in fish, including vitellogenin (VTG) synthesis and gonadal …
17-β-Estradiol: Significant reduction of its toxicity in water treated by photocatalysis
L Orozco-Hernández, LM Gómez-Oliván… - Science of The Total …, 2019 - Elsevier
The aim of this study was to assess the efficiency of photocatalysis by TiO 2 on the removal
of 17-β-estradiol (E2)(at environmentally relevant concentrations) and the toxicity caused by …
of 17-β-estradiol (E2)(at environmentally relevant concentrations) and the toxicity caused by …
Modeling effects of mixtures of endocrine disrupting chemicals at the river catchment scale
JP Sumpter, AC Johnson, RJ Williams… - … science & technology, 2006 - ACS Publications
For endocrine disrupting chemicals in the environment, concerns arise primarily from the
effects that may be induced in wildlife. A well studied example is estrogenic chemicals in the …
effects that may be induced in wildlife. A well studied example is estrogenic chemicals in the …