Background Substance use disorder (SUD) remains a significant public health issue. A
greater understanding of how genes and environment interact to regulate phenotypes …

The purpose of this review is to present up-to-date pharmacological, genetic, and behavioral
findings from the alcohol-preferring P rat and summarize similar past work. Behaviorally, the …

Neuronal alternative splicing is a key gene regulatory mechanism in the brain. However, the
spliceosome machinery is insufficient to fully specify splicing complexity. In considering the …

Background Cocaine dependence has been associated with alterations in the brain's white
matter integrity, yet relevant questions remain about what alterations are linked to cocaine …

Background Animal and human studies indicate that GABBR 1, encoding the GABAB 1
receptor subunit, and SLC 6A1, encoding the neuronal gamma‐aminobutyric acid (GABA) …

Medication-assisted behavior treatment for alcohol use disorder (AUD) holds promise to
enhance the efficacy of medication and of behavior therapy when administered individually …

Alcohol use disorder (AUD) is a prevalent neuropsychiatric disorder that is a major global
health concern, affecting millions of people worldwide. Past molecular studies of AUD used …

Substance-related disorders are a group of medical conditions that affect a person's brain
and behavior and lead to an inability to control the use of legal or illegal drug (s) or …

Alcohol morphopathology has been studied over time, being a central interest of specialists,
due to the negative consequences it has on the brain and the entire central nervous system …

Alkohol etylowy jest spożywany w nieomal każdym społeczeństwie, a jego popularność
wynika głównie z faktu, że jest łatwy w produkcji, najmniej toksyczny spośród alkoholi …