Toxic interactions between dopamine, α-synuclein, monoamine oxidase, and genes in mitochondria of Parkinson's disease

M Naoi, W Maruyama, M Shamoto-Nagai… - Journal of Neural …, 2024 - Springer
Parkinson's disease is characterized by its distinct pathological features; loss of dopamine
neurons in the substantia nigra pars compacta and accumulation of Lewy bodies and Lewy …

[HTML][HTML] Relaxation of mitochondrial hyperfusion in the diabetic retina via N6-furfuryladenosine confers neuroprotection regardless of glycaemic status

A Anderson, N Alfahad, D Wimalachandra… - Nature …, 2024 - nature.com
The recovery of mitochondrial quality control (MQC) may bring innovative solutions for
neuroprotection, while imposing a significant challenge given the need of holistic …

Interaction of PINK1 with nucleotides and kinetin

ZY Gan, S Callegari, TN Nguyen, NS Kirk, A Leis… - Science …, 2024 - science.org
The ubiquitin kinase PINK1 accumulates on damaged mitochondria to trigger mitophagy,
and PINK1 loss-of-function mutations cause early onset Parkinson's disease. Nucleotide …

Parkinson's disease: Are PINK1 activators inching closer to the clinic?

Y Mehellou - ACS Medicinal Chemistry Letters, 2023 - ACS Publications
The activation of PINK1 by small molecules has emerged as a promising strategy in treating
Parkinson's disease (PD). Recent progress in this area has raised excitement around PINK1 …

Forsythiaside A attenuates mastitis via PINK1/Parkin-mediated mitophagy

J Liu, Y Gao, H Zhang, Z Hao, G Zhou, H Wen, Q Su… - Phytomedicine, 2024 - Elsevier
Background Bovine mastitis is the most common animal production disease in the global
dairy industry, which affects the health of dairy cows. When bovine mastitis occurs, the …

Relaxation of mitochondrial hyperfusion in the diabetic retina via N6-furfuryladenine confers neuroprotection regardless of glycaemic status.

A Anderson, N Alfahad, D Wimalachandra, K Bouzinab… - 2023 - researchsquare.com
The recovery of mitochondrial quality control (MQC) may bring innovative solutions for
neuroprotection, while also imposing an extraordinary challenge given the need of holistic …