The chloride importer NKCC1 and the chloride exporter KCC2 are key regulators of
neuronal chloride concentration. A defective NKCC1/KCC2 expression ratio is associated …

Simple Summary Fiber pathways that descend from the brain to the spinal cord drive motor
behavior and modulate incoming sensory signals and the capacity to change (plasticity). A …

High spinal cord injuries (SCIs) lead to permanent functional deficits, including respiratory
dysfunction. Patients living with such conditions often rely on ventilatory assistance to …

Cervical spinal injury is typically associated with respiratory impairments due to damage to
bulbospinal respiratory pathways and phrenic motoneurons. Magnetic stimulation is a non …

Cervical spinal cord injury (cSCI) severs bulbospinal projections to respiratory motor
neurons, paralyzing respiratory muscles below the injury. C2 spinal hemisection (C2Hx) is a …

Correct operation of neuronal networks depends on the interplay between synaptic
excitation and inhibition processes leading to a dynamic state termed balanced network. In …

Although cervical spinal cord injury (cSCI) disrupts bulbo-spinal serotonergic projections,
partial recovery of spinal serotonergic innervation below the injury site is observed after …

During development, GABA and glycine play major trophic and synaptic roles in the
establishment of the neuromotor system. In this review, we summarise the formation …

Abstract Low-dose (< 2 h/day), acute intermittent hypoxia (AIH) elicits multiple forms of
serotonin-dependent phrenic motor plasticity and is emerging as a promising therapeutic …

More than half of all spinal cord injuries (SCIs) occur at the cervical level and often lead to
life-threatening breathing motor dysfunction. The C2 hemisection (C2Hx) and high cervical …