Gut microbiota influence immunotherapy responses: mechanisms and therapeutic strategies

Y Lu, X Yuan, M Wang, Z He, H Li, J Wang… - Journal of hematology & …, 2022 - Springer
The gut microbiota have long been recognized to play a key role in human health and
disease. Currently, several lines of evidence from preclinical to clinical research have …

TLR4 and CD14 trafficking and its influence on LPS-induced pro-inflammatory signaling

A Ciesielska, M Matyjek, K Kwiatkowska - Cellular and molecular life …, 2021 - Springer
Abstract Toll-like receptor (TLR) 4 belongs to the TLR family of receptors inducing pro-
inflammatory responses to invading pathogens. TLR4 is activated by lipopolysaccharide …

Autoimmune and autoinflammatory conditions after COVID-19 vaccination. New case reports and updated literature review

Y Rodríguez, M Rojas, S Beltrán, F Polo… - Journal of …, 2022 - Elsevier
Autoimmunity linked to COVID-19 immunization has been recorded throughout the
pandemic. Herein we present six new patients who experienced relapses of previous …

[HTML][HTML] Do COVID-19 RNA-based vaccines put at risk of immune-mediated diseases? In reply to “potential antigenic cross-reactivity between SARS-CoV-2 and …

R Talotta - Clinical Immunology (Orlando, Fla.), 2021 - ncbi.nlm.nih.gov
I read with great interest the article by Vojdani et al.[1], concerning the hypothesis of a
molecular mimicry mechanism between the nucleoprotein/spike protein of Severe Acute …

cGAS in action: Expanding roles in immunity and inflammation

A Ablasser, ZJ Chen - Science, 2019 - science.org
BACKGROUND The life of any organism depends on the ability of cells to accurately
recognize and eliminate harmful microbes. To detect the immense repertoire of pathogenic …

UNC93B1 variants underlie TLR7-dependent autoimmunity

C Wolf, EL Lim, M Mokhtari, B Kind, A Odainic… - Science …, 2024 - science.org
UNC93B1 is critical for trafficking and function of nucleic acid–sensing Toll-like receptors
(TLRs) TLR3, TLR7, TLR8, and TLR9, which are essential for antiviral immunity. Overactive …

RIG-I and other RNA sensors in antiviral immunity

KT Chow, M Gale Jr, YM Loo - Annual review of immunology, 2018 - annualreviews.org
Pattern recognition receptors (PRRs) survey intra-and extracellular spaces for pathogen-
associated molecular patterns (PAMPs) within microbial products of infection. Recognition …

Recognition of endogenous nucleic acids by the innate immune system

A Roers, B Hiller, V Hornung - Immunity, 2016 - cell.com
Recognition of DNA and RNA by endosomal and cytosolic sensors constitutes a central
element in the detection of microbial invaders by the innate immune system. However, the …

[HTML][HTML] COVID-19 recombinant mRNA vaccines and serious ocular inflammatory side effects: real or coincidence?

A Maleki, S Look-Why, A Manhapra… - Journal of ophthalmic & …, 2021 - ncbi.nlm.nih.gov
COVID-19 Recombinant mRNA Vaccines and Serious Ocular Inflammatory Side Effects: Real or
Coincidence? - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …

Distinct and orchestrated functions of RNA sensors in innate immunity

GQ Liu, MU Gack - Immunity, 2020 - cell.com
Faithful maintenance of immune homeostasis relies on the capacity of the cellular immune
surveillance machinery to recognize" nonself", such as the presence of pathogenic RNA …