Antiphospholipid syndrome

K Schreiber, S Sciascia, PG De Groot… - Nature reviews Disease …, 2018 - nature.com
Antiphospholipid syndrome (APS) is an autoimmune disease characterized by the presence
of antiphospholipid antibodies, such as lupus anticoagulant, anticardiolipin antibodies and …

Diagnosis and management of the antiphospholipid syndrome

D Garcia, D Erkan - New England Journal of Medicine, 2018 - Mass Medical Soc
Antiphospholipid Syndrome Antiphospholipid antibodies can induce endothelial-cell,
complement, platelet, neutrophil, and monocyte activation, leading to thrombosis, renal …

[HTML][HTML] EULAR recommendations for women's health and the management of family planning, assisted reproduction, pregnancy and menopause in patients with …

L Andreoli, GK Bertsias, N Agmon-Levin… - Annals of the …, 2017 - ard.bmj.com
Objectives Develop recommendations for women9s health issues and family planning in
systemic lupus erythematosus (SLE) and/or antiphospholipid syndrome (APS). Methods …

Tumor necrosis factor-alpha and pregnancy: focus on biologics. An updated and comprehensive review

J Alijotas-Reig, E Esteve-Valverde… - Clinical reviews in …, 2017 - Springer
Tumor necrosis factor-α (TNF-α) is a central regulator of inflammation, and TNF-α
antagonists may be effective in treating inflammatory disorders in which TNF-α plays a major …

Antiphospholipid antibody profile based obstetric outcomes of primary antiphospholipid syndrome: the PREGNANTS study

G Saccone, V Berghella, GM Maruotti, T Ghi… - American journal of …, 2017 - Elsevier
Background Antiphospholipid syndrome is an autoimmune, hypercoagulable state that is
caused by antiphospholipid antibodies. Anticardiolipin antibodies, anti-β2 glycoprotein-I …

[HTML][HTML] Pregnancy outcome predictors in antiphospholipid syndrome: A systematic review and meta-analysis

IJ Walter, MJK Haneveld, AT Lely… - Autoimmunity …, 2021 - Elsevier
Objective To identify and assess the magnitude of effect of pregnancy outcome predictors in
women with antiphospholipid syndrome (APS) by means of systematic review and meta …

The efficacy of hydroxychloroquine for obstetrical outcome in anti-phospholipid syndrome: data from a European multicenter retrospective study

A Mekinian, MG Lazzaroni, A Kuzenko… - Autoimmunity …, 2015 - Elsevier
In European multicenter study, we aimed to describe the real-life hydroxychloroquine use in
APS patients during pregnancy and determine its benefit in refractory obstetrical APS. We …

Obstetric and vascular antiphospholipid syndrome: same antibodies but different diseases?

PL Meroni, MO Borghi, C Grossi… - Nature Reviews …, 2018 - nature.com
Recurrent thrombosis and miscarriages are the main clinical manifestations of
antiphospholipid syndrome (APS). Although most patients display both clinical signs, some …

Pregnancy in systemic lupus erythematosus and antiphospholipid syndrome

R Fischer-Betz, C Specker - Best practice & research Clinical rheumatology, 2017 - Elsevier
Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease with a
high prevalence in females of childbearing age. Pregnancy in SLE nowadays has favorable …

Lupus anticoagulant is the main predictor of adverse pregnancy outcomes in aPL-positive patients: validation of PROMISSE study results

CM Yelnik, CA Laskin, TF Porter, DW Branch… - Lupus science & …, 2016 - lupus.bmj.com
Objective We previously reported that lupus anticoagulant (LAC) is the main predictor of
poor pregnancy outcome in antiphospholipid antibody (aPL)-positive patients. We sought to …