Glioblastoma is the most common brain cancer in adults and presents a major challenge for
targeted drug delivery due to the blood-brain barrier (BBB) and the highly infiltrative growth …

Cell manipulation is the foundation of biochemical studies, which demands user-friendly,
multifunctional and precise tools. Based on flow confinement principles, open microfluidics …

Cell migration is crucial for many biological processes, including normal development,
immune response, and tissue homeostasis and many pathological processes such as …

Microfluidic systems offer versatile biomedical tools and methods to enhance human
convenience and health. Advances in these systems enables next-generation microfluidics …

In this work, for first time, circulating tumor cells (CTCs) are captured on an open
biofunctionalized substrate with multiplexing capability. This is achieved by developing a …

In this work, we fabricate microfluidic probes (MFPs) in a single step by stereolithographic
3D printing and benchmark their performance with standard MFPs fabricated via glass or …

Microfluidic multipoles (MFMs) have been realized experimentally and hold promise for
“open-space” biological and chemical surface processing. Whereas convective flow can …

While many tools exist to study immune‐cell chemotaxis in vitro, current methods often lack
desirable features. Using fluid‐walled microfluidics, circuits are built around primary murine …

The laminar flow profiles in microfluidic systems coupled to rapid diffusion at flow
streamlines have been widely utilized to create well-controlled chemical gradients in cell …

Immune surveillance is dependent on lymphocyte migration and targeted recruitment. This
can involve different modes of cell motility ranging from random walk to highly directional …