[HTML][HTML] The use of genomics, proteomics, and metabolomics in identifying biomarkers of male infertility

JR Kovac, AW Pastuszak, DJ Lamb - Fertility and sterility, 2013 - Elsevier
Although male factors account for approximately 50% of all infertility, the mechanisms
underlying their origin are unknown. Currently, clinicians rely primarily on semen analyses …

[HTML][HTML] Towards a multi-omics of male infertility

AO Wagner, A Turk, T Kunej - The world journal of men's health, 2023 - ncbi.nlm.nih.gov
Infertility is a common problem affecting one in six couples and in 30% of infertile couples,
the male factor is a major cause. A large number of genes are involved in spermatogenesis …

Proteomics, oxidative stress and male infertility

A Agarwal, D Durairajanayagam, J Halabi… - Reproductive …, 2014 - Elsevier
Oxidative stress has been established as one of the main causes of male infertility and has
been implicated in many diseases associated with infertile men. It results from high …

Proteomic analysis of seminal fluid from men exhibiting oxidative stress

R Sharma, A Agarwal, G Mohanty… - Reproductive Biology …, 2013 - Springer
Background Seminal plasma serves as a natural reservoir of antioxidants. It helps to remove
excessive formation of reactive oxygen species (ROS) and consequently, reduce oxidative …

Investigation of male infertility using quantitative comparative proteomics

C Légaré, A Droit, F Fournier, S Bourassa… - Journal of proteome …, 2014 - ACS Publications
Male factors account for 40% of infertility cases. The identification of differentially expressed
proteins on spermatozoa from fertile and infertile men can help in the elucidation of the …

[HTML][HTML] Prolactin-induced protein (PIP)-characterization and role in breast cancer progression

A Urbaniak, K Jablonska… - American journal of …, 2018 - ncbi.nlm.nih.gov
Prolactin-induced protein (PIP) is a small secreted glycoprotein carrying several N-linked
carbohydrate chains. The expression of PIP is generally restricted to cells with apocrine …

Identification of putative fertility markers in seminal plasma of crossbred bulls through differential proteomics

MKM Aslam, A Kumaresan, VK Sharma, M Tajmul… - Theriogenology, 2014 - Elsevier
Sub-fertility is a major problem in crossbred bulls leading to disintegration of breeding
systems and huge economic loss. Identification of some potential biomarkers to determine …

Proteomic changes in human spermatozoa during in vitro capacitation and acrosome reaction in normozoospermia and asthenozoospermia

N Chhikara, AK Tomar, SK Datta, S Yadav - Andrology, 2023 - Wiley Online Library
Background The cellular and molecular mechanisms of the events that help spermatozoa
acquire their fertilizing capability during capacitation and acrosome reaction are not …

[HTML][HTML] Novel FFPE proteomics method suggests prolactin induced protein as hormone induced cytoskeleton remodeling spatial biomarker

J Faktor, S Kote, M Bienkowski, TR Hupp… - Communications …, 2024 - nature.com
Robotically assisted proteomics provides insights into the regulation of multiple proteins
achieving excellent spatial resolution. However, developing an effective method for spatially …

Proteome of cat semen obtained after urethral catheterization

M Mogielnicka-Brzozowska, S Prochowska, W Niżański… - Theriogenology, 2020 - Elsevier
The binding of seminal plasma (SP) proteins by spermatozoa plays an important role in the
regulation of sperm epididymal maturation, motility gaining in female reproductive tracts and …