[HTML][HTML] Polyamine Metabolism in Leishmania Parasites: A Promising Therapeutic Target

NS Carter, Y Kawasaki, SS Nahata, S Elikaee… - Medical …, 2022 - mdpi.com
Parasites of the genus Leishmania cause a variety of devastating and often fatal diseases in
humans and domestic animals worldwide. The need for new therapeutic strategies is urgent …

Promising natural products for the treatment of cutaneous leishmaniasis: A review of in vitro and in vivo studies

RC Afonso, RMK Yien, LBO de Siqueira… - Experimental …, 2023 - Elsevier
Although there are available treatments for cutaneous leishmaniasis (CL), the drugs used
are far from ideal, toxic, and costly, in addition to the challenge faced by the development of …

[HTML][HTML] Vaccine value profile for leishmaniasis

PM Kaye, G Matlashewski, S Mohan, E Le Rutte… - vaccine, 2023 - Elsevier
Leishmania infections are global, occurring in 98 countries and all World Health
Organization (WHO) regions with 600 million to 1 billion people at risk of infection. Visceral …

[HTML][HTML] Tegumentary leishmaniasis in Northeastern Italy from 2017 to 2020: a neglected public health issue

V Gaspari, T Gritti, M Ortalli, A Santi, G Galletti… - International Journal of …, 2022 - mdpi.com
Tegumentary leishmaniasis (TL) includes cutaneous (CL) and mucosal (ML) leishmaniasis;
despite being endemic in southern Europe, it is often underdiagnosed and underreported …

A prospective longitudinal study on the elimination trend of rural cutaneous leishmaniasis in southeastern Iran: climate change, population displacement, and …

M Bamorovat, I Sharifi, MR Aflatoonian… - Science of the Total …, 2024 - Elsevier
Leishmaniasis is a complex disease. Any change in weather conditions affects the humans'
social and agricultural expansion and, consequently, the parasite's life cycle in terms of …

[HTML][HTML] Epidemiological, clinical and hematological profiles of visceral leishmaniasis among patients visiting Tefera Hailu Memorial Hospital, Northeast Ethiopia: a 4 …

H Debash, H Bisetegn, M Nigatie, G Abeje… - Scientific Reports, 2023 - nature.com
Visceral leishmaniasis is a major, life-threatening parasitic disease that still remains a
serious public health problem in Ethiopia. Understanding the epidemiological, clinical, and …

Social determinants of visceral leishmaniasis elimination in Eastern Africa

J Alvar, MT Beca-Martínez, D Argaw, S Jain… - BMJ Global …, 2023 - gh.bmj.com
Visceral leishmaniasis is a vector-borne, protozoan disease with severe public health
implications. Following the successful implementation of an elimination programme in South …

Prevalence, assessment and correlates of mental health problems in neglected tropical diseases: a systematic review

S Adjorlolo, EE Adimado, M Setordzi… - International …, 2024 - academic.oup.com
Neglected tropical diseases (NTDs) are a group of disease conditions that affect the world's
poorest people in low-and middle-income countries. NTDs are associated with negative …

Revolutionizing Leishmaniasis Treatment with Cutting Edge Drug Delivery Systems and Nanovaccines: An Updated Review

S Tambe, S Nag, SR Pandya, R Kumar… - ACS Infectious …, 2024 - ACS Publications
Leishmaniasis, one of the most overlooked tropical diseases, is a life-threatening illness
caused by the parasite Leishmania donovani that is prevalent in underdeveloped nations …

[HTML][HTML] Recent advances in surface plasmon resonance as a powerful approach for studying Leishmania spp. and Trypanosoma cruzi parasites

F Farshchi, G Dias-Lopes, LM Castro-Côrtes, CR Alves… - Talanta Open, 2023 - Elsevier
Leishmaniases and Chagas disease pose significant health challenges, particularly in
tropical regions among impoverished communities. These conditions prevail in areas …