Quantitative elastography methods in liver disease: current evidence and future directions

P Kennedy, M Wagner, L Castéra, CW Hong… - Radiology, 2018 - pubs.rsna.org
Chronic liver diseases often result in the development of liver fibrosis and ultimately,
cirrhosis. Treatment strategies and prognosis differ greatly depending on the severity of liver …

[HTML][HTML] Oxidative stress in cancer and fibrosis: Opportunity for therapeutic intervention with antioxidant compounds, enzymes, and nanoparticles

J Morry, W Ngamcherdtrakul, W Yantasee - Redox biology, 2017 - Elsevier
Oxidative stress, mainly contributed by reactive oxygen species (ROS), has been implicated
in pathogenesis of several diseases. We review two primary examples; fibrosis and cancer …

[HTML][HTML] Animal and organoid models of liver fibrosis

Y Bao, L Wang, H Pan, T Zhang, Y Chen, S Xu… - Frontiers in …, 2021 - frontiersin.org
Liver fibrosis refers to the process underlying the development of chronic liver diseases,
wherein liver cells are repeatedly destroyed and regenerated, which leads to an excessive …

Liver fibrosis: Review of current imaging and MRI quantification techniques

L Petitclerc, G Sebastiani, G Gilbert… - Journal of Magnetic …, 2017 - Wiley Online Library
Liver fibrosis is characterized by the accumulation of extracellular matrix proteins such as
collagen in the liver interstitial space. All causes of chronic liver disease may lead to fibrosis …

[HTML][HTML] Mechanisms underlying hepatitis C virus-associated hepatic fibrosis

M Khatun, RB Ray - Cells, 2019 - mdpi.com
Hepatitis C virus (HCV) infection often causes liver diseases, including fibrosis, cirrhosis and
hepatocellular carcinoma (HCC). Liver fibrosis is the outcome of the wound healing …

Liver surface nodularity quantification from routine CT images as a biomarker for detection and evaluation of cirrhosis

AD Smith, CR Branch, K Zand, C Subramony, H Zhang… - Radiology, 2016 - pubs.rsna.org
Purpose To determine the accuracy, reproducibility, and intra-and interobserver agreement
of a computer-based quantitative method to measure liver surface nodularity (LSN) from …

Direct-acting antiviral therapy for chronic HCV infection results in liver stiffness regression over 12 months post-treatment

J Chan, N Gogela, H Zheng, S Lammert, T Ajayi… - Digestive diseases and …, 2018 - Springer
Background Liver fibrosis stage determines risk of morbidity and mortality from chronic
hepatitis C virus (HCV) infection. Prior data have shown long-term reversal of liver fibrosis …

Xiaoyaosan decoction alleviated rat liver fibrosis via the TGFβ/Smad and Akt/FoxO3 signaling pathways based on network pharmacology analysis

Y Zhou, R Wu, FF Cai, WJ Zhou, YY Lu, H Zhang… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Liver fibrosis is an outcome of many chronic liver diseases
and often results in cirrhosis, liver failure, and even hepatocarcinoma. Xiaoyaosan decoction …

Acoustic Radiation Force Impulse (ARFI) Elastography for non‑invasive evaluation of hepatic fibrosis in chronic hepatitis B and C patients: a systematic review and …

X Hu, L Qiu, D Liu, L Qian - Medical Ultrasonography, 2017 - medultrason.ro
Aim: The purpose of the study was to assess the effect of Acoustic Radiation Force Impulse
(ARFI) elastography in the diagnosis of liver fibrosis in chronic hepatitis B and C patients …

Intelligent liver function testing (iLFT): a trial of automated diagnosis and staging of liver disease in primary care

JF Dillon, MH Miller, EM Robinson, A Hapca… - Journal of …, 2019 - Elsevier
Background & Aims Liver function tests (LFTs) are frequently requested blood tests which
may indicate liver disease. LFTs are commonly abnormal, the causes of which can be …