The neurobiology of SARS-CoV-2 infection
J Meinhardt, S Streit, C Dittmayer, RV Manitius… - Nature Reviews …, 2024 - nature.com
Worldwide, over 694 million people have been infected with SARS-CoV-2, with an estimated
55–60% of those infected developing COVID-19. Since the beginning of the pandemic in …
55–60% of those infected developing COVID-19. Since the beginning of the pandemic in …
Olfactory immune response to SARS-CoV-2
SA Wellford, EA Moseman - Cellular & Molecular Immunology, 2024 - nature.com
Numerous pathogens can infect the olfactory tract, yet the pandemic caused by SARS-CoV-
2 has strongly emphasized the importance of the olfactory mucosa as an immune barrier …
2 has strongly emphasized the importance of the olfactory mucosa as an immune barrier …
SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein
Abstract Coronavirus disease-2019 (COVID-19) is primarily a respiratory disease, however,
an increasing number of reports indicate that SARS-CoV-2 infection can also cause severe …
an increasing number of reports indicate that SARS-CoV-2 infection can also cause severe …
Full protection from SARS-CoV-2 brain infection and damage in susceptible transgenic mice conferred by MVA-CoV2-S vaccine candidate
J Villadiego, J García-Arriaza, R Ramírez-Lorca… - Nature …, 2023 - nature.com
Vaccines against SARS-CoV-2 have been shown to be safe and effective but their protective
efficacy against infection in the brain is yet unclear. Here, in the susceptible transgenic K18 …
efficacy against infection in the brain is yet unclear. Here, in the susceptible transgenic K18 …
Age-dependent acquisition of pathogenicity by SARS-CoV-2 Omicron BA. 5
Pathology studies of SARS-CoV-2 Omicron variants of concern (VOC) are challenged by the
lack of pathogenic animal models. While Omicron BA. 1 and BA. 2 replicate in K18-hACE2 …
lack of pathogenic animal models. While Omicron BA. 1 and BA. 2 replicate in K18-hACE2 …
Olfactory immunology: the missing piece in airway and CNS defence
SA Wellford, EA Moseman - Nature Reviews Immunology, 2024 - nature.com
The olfactory mucosa is a component of the nasal airway that mediates the sense of smell.
Recent studies point to an important role for the olfactory mucosa as a barrier to both …
Recent studies point to an important role for the olfactory mucosa as a barrier to both …
In vitro and in vivo differences in neurovirulence between D614G, Delta And Omicron BA. 1 SARS-CoV-2 variants
L Bauer, M Rissmann, FFW Benavides… - Acta neuropathologica …, 2022 - Springer
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with
various neurological complications. Although the mechanism is not fully understood, several …
various neurological complications. Although the mechanism is not fully understood, several …
[HTML][HTML] The Fc-effector function of COVID-19 convalescent plasma contributes to SARS-CoV-2 treatment efficacy in mice
I Ullah, G Beaudoin-Bussières, K Symmes… - Cell Reports …, 2023 - cell.com
Summary COVID-19 convalescent plasmas (CCPs) are chosen for plasma therapy based on
neutralizing titers and anti-Spike immunoglobulin levels. However, CCP characteristics that …
neutralizing titers and anti-Spike immunoglobulin levels. However, CCP characteristics that …
Neuropathological features of SARS-CoV-2 delta and omicron variants
E Normandin, N Valizadeh, EA Rudmann… - … of Neuropathology & …, 2023 - academic.oup.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is continually evolving
resulting in variants with increased transmissibility, more severe disease, reduced …
resulting in variants with increased transmissibility, more severe disease, reduced …
Delayed tumor-draining lymph node irradiation preserves the efficacy of combined radiotherapy and immune checkpoint blockade in models of metastatic disease
I Telarovic, CSM Yong, L Kurz, I Vetrugno… - Nature …, 2024 - nature.com
Cancer resistance to immune checkpoint inhibitors motivated investigations into leveraging
the immunostimulatory properties of radiotherapy to overcome immune evasion and to …
the immunostimulatory properties of radiotherapy to overcome immune evasion and to …