Our window to the world is provided by the cornea on the front surface of the eye. The
integrity and functionality of the outermost corneal epithelium is essential for vision. A …

Limbal stem cell deficiency (LSCD) is a complex blinding disease of the cornea, which
cannot be treated with conventional corneal transplants. Instead, a stem cell (SC) graft is …

Purpose.: To evaluate the effect of conditioned medium from human uterine cervical stem
cells (CM-hUCESCs) on corneal epithelial healing in a rat model of dry eye after alkaline …

Purpose: Differentiated from adult stem cells (ASCs), transit-amplifying cells (TACs) play an
important role in tissue homeostasis, development, and regeneration. This study aimed to …

Maintenance of the visual function is the desired outcome of ophthalmologic therapies. The
shortcomings of the current treatment options, like partial recovery, post-operation failure …

The condition of the corneal epithelium is a critical determinant of corneal transparency and
clear vision. The corneal epithelium serves as a barrier to protect the eye from external …

Purpose: A chemical approach to examine the role of Wnt signaling in maintaining the
stemness and/or proliferation of limbal stem/progenitor cells (LSCs). Methods: LSCs were …

Collagen fibrils are homogeneous in diameter and are aligned at a constant distance from
each other to maintain tissue transparency. Keratocytes are the resident cells of the stroma …

Stem cells are unspecialized cells that have been a major focus of the field of regenerative
medicine, opening new frontiers and regarded as the future of medicine. The ophthalmology …

A simple, reproducible, animal-material free method for cultivating and characterizing
cornea limbal epithelial stem cells (LESCs) on human lens capsule (LC) was developed for …