Pathogenesis of human cytomegalovirus in the immunocompromised host

P Griffiths, M Reeves - Nature Reviews Microbiology, 2021 - nature.com
Human cytomegalovirus (HCMV) is a herpesvirus that infects~ 60% of adults in developed
countries and more than 90% in developing countries. Usually, it is controlled by a vigorous …

The third international consensus guidelines on the management of cytomegalovirus in solid-organ transplantation

CN Kotton, D Kumar, AM Caliendo, S Huprikar… - …, 2018 - journals.lww.com
Despite recent advances, cytomegalovirus (CMV) infections remain one of the most common
complications affecting solid organ transplant recipients, conveying higher risks of …

Maribavir for refractory cytomegalovirus infections with or without resistance post-transplant: results from a phase 3 randomized clinical trial

RK Avery, S Alain, BD Alexander… - Clinical Infectious …, 2022 - academic.oup.com
Background Therapies for refractory cytomegalovirus infections (with or without resistance
[R/R]) in transplant recipients are limited by toxicities. Maribavir has multimodal anti …

Letermovir vs valganciclovir for prophylaxis of cytomegalovirus in high-risk kidney transplant recipients: a randomized clinical trial

AP Limaye, K Budde, A Humar, F Vincenti… - Jama, 2023 - jamanetwork.com
Importance Valganciclovir for 200 days is standard care for cytomegalovirus (CMV)
prophylaxis in high-risk CMV-seronegative kidney transplant recipients who receive an …

Cytomegalovirus in solid organ transplant recipients—Guidelines of the American Society of Transplantation Infectious Diseases Community of Practice

RR Razonable, A Humar - Clinical transplantation, 2019 - Wiley Online Library
Cytomegalovirus (CMV) is one of the most common opportunistic infections that affect the
outcome of solid organ transplantation. This updated guideline from the American Society of …

Guidelines for the management of cytomegalovirus infection in patients with haematological malignancies and after stem cell transplantation from the 2017 European …

P Ljungman, R de la Camara, C Robin… - The Lancet infectious …, 2019 - thelancet.com
Cytomegalovirus is one of the most important infections to occur after allogeneic
haematopoietic stem cell transplantation (HSCT), and an increasing number of reports …

Survival, nonrelapse mortality, and relapse-related mortality after allogeneic hematopoietic cell transplantation: comparing 2003–2007 versus 2013–2017 cohorts

GB McDonald, BM Sandmaier, M Mielcarek… - Annals of internal …, 2020 - acpjournals.org
Background: Allogeneic hematopoietic cell transplantation is indicated for refractory
hematologic cancer and some nonmalignant disorders. Survival is limited by recurrent …

Diagnosis of severe respiratory infections in immunocompromised patients

E Azoulay, L Russell, A Van de Louw, V Metaxa… - Intensive care …, 2020 - Springer
An increasing number of critically ill patients are immunocompromised. Acute hypoxemic
respiratory failure (ARF), chiefly due to pulmonary infection, is the leading reason for ICU …

Posttransplant cyclophosphamide is associated with increased cytomegalovirus infection: a CIBMTR analysis

SR Goldsmith, MB Abid, JJ Auletta… - Blood, The Journal …, 2021 - ashpublications.org
Prior studies suggest increased cytomegalovirus (CMV) infection after haploidentical donor
transplantation with posttransplant cyclophosphamide (HaploCy). The role of allograft …

[HTML][HTML] American Society for Transplantation and Cellular Therapy series:# 3—prevention of cytomegalovirus infection and disease after hematopoietic cell …

M Hakki, SL Aitken, L Danziger-Isakov… - … and Cellular Therapy, 2021 - Elsevier
Abstract The Practice Guidelines Committee of the American Society for Transplantation and
Cellular Therapy partnered with its Transplant Infectious Disease Special Interest Group to …