[HTML][HTML] Epidemiology of glioblastoma multiforme–literature review

S Grochans, AM Cybulska, D Simińska, J Korbecki… - Cancers, 2022 - mdpi.com
Simple Summary Glioblastoma multiforme (GBM) is one of the most aggressive
malignancies, accounting for 14.5% of all central nervous system tumors and 48.6% of …

[HTML][HTML] Autophagy: Regulator of cell death

SZ Liu, SJ Yao, H Yang, SJ Liu, YJ Wang - Cell death & disease, 2023 - nature.com
Autophagy is the process by which cells degrade and recycle proteins and organelles to
maintain intracellular homeostasis. Generally, autophagy plays a protective role in cells, but …

Sphingolipids and their metabolism in physiology and disease

YA Hannun, LM Obeid - Nature reviews Molecular cell biology, 2018 - nature.com
Studies of bioactive lipids in general and sphingolipids in particular have intensified over the
past several years, revealing an unprecedented and unanticipated complexity of the …

Neuronal cell death

M Fricker, AM Tolkovsky, V Borutaite… - Physiological …, 2018 - journals.physiology.org
Neuronal cell death occurs extensively during development and pathology, where it is
especially important because of the limited capacity of adult neurons to proliferate or be …

Lysosomal membrane permeabilization and cell death

F Wang, R Gómez‐Sintes, P Boya - Traffic, 2018 - Wiley Online Library
Lysosomes are membrane‐enclosed organelles that mediate the intracellular degradation
of macromolecules. They play an essential role in calcium regulation and have emerged as …

Sphingolipid metabolism in cancer signalling and therapy

B Ogretmen - Nature Reviews Cancer, 2018 - nature.com
Sphingolipids, including the two central bioactive lipids ceramide and sphingosine-1-
phosphate (S1P), have opposing roles in regulating cancer cell death and survival …

[HTML][HTML] Anti-cancer potential of cannabinoids, terpenes, and flavonoids present in cannabis

AM Tomko, EG Whynot, LD Ellis, DJ Dupré - Cancers, 2020 - mdpi.com
In recent years, and even more since its legalization in several jurisdictions, cannabis and
the endocannabinoid system have received an increasing amount of interest related to their …

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif… - autophagy, 2021 - Taylor & Francis
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

[HTML][HTML] Cannabinoids in the landscape of cancer

N Mangal, S Erridge, N Habib, A Sadanandam… - Journal of cancer …, 2021 - Springer
Introduction Cannabinoids are a group of terpenophenolic compounds derived from the
Cannabis sativa L. plant. There is a growing body of evidence from cell culture and animal …

[HTML][HTML] Regulation of autophagy via carbohydrate and lipid metabolism in cancer

J Alizadeh, M Kavoosi, N Singh, S Lorzadeh… - Cancers, 2023 - mdpi.com
Simple Summary The metabolism of carbohydrates and lipids is essential to meet the
diverse needs of cells. The autophagy cellular pathway is crucial for normal cellular function …