The benefits and risks of statin therapy in ischemic stroke: a review of the literature

W Zhao, ZJ Xiao, SP Zhao - Neurology India, 2019 - journals.lww.com
Statins are effective cholesterol-lowering drugs for reducing the risks of mortality and
morbidity of cardiovascular diseases. Increasing evidence has shown that statin use is …

[HTML][HTML] A comparative study of high-intensity rosuvastatin versus atorvastatin therapy post-acute coronary syndrome using real-world data

A Rahhal, F Khir, B Orabi, S Chbib, O Al-Khalaila… - Current Problems in …, 2022 - Elsevier
A high-intensity statin is recommended for the secondary prevention of cardiovascular
diseases (CVD). However, real-world evidence of the effectiveness of rosuvastatin following …

[HTML][HTML] Developing WHO guidelines: time to formally include evidence from mathematical modelling studies

M Egger, L Johnson, C Althaus, A Schöni… - …, 2017 - ncbi.nlm.nih.gov
In recent years, the number of mathematical modelling studies has increased steeply. Many
of the questions addressed in these studies are relevant to the development of World Health …

Effect of a single high loading dose of rosuvastatin on percutaneous coronary intervention for acute coronary syndromes

Z Wang, H Dai, M Xing, Z Yu, X Lin… - Journal of …, 2013 - journals.sagepub.com
Objectives: A high loading dose of atorvastatin has been confirmed to reduce
postprocedural events in patients undergoing percutaneous coronary intervention (PCI). In …

GetReal in mathematical modelling: a review of studies predicting drug effectiveness in the real world

K Panayidou, S Gsteiger, M Egger… - Research synthesis …, 2016 - Wiley Online Library
The performance of a drug in a clinical trial setting often does not reflect its effect in daily
clinical practice. In this third of three reviews, we examine the applications that have been …

Is statin therapy after ischaemic stroke associated with increased intracerebral hemorrhage? The association may be dependent on intensity of statin therapy

R Yang, J Wu, H Yu, S Wang, H Chen… - … Journal of Stroke, 2023 - journals.sagepub.com
Background: There has been concern that statin therapy may be associated with an
increased risk of intracerebral hemorrhage (ICH). We investigated whether the intensity and …

[HTML][HTML] Comparison of the Efficacy of Atorvastatin with Rosuvastatin in Preventing Cardiovascular Events Among Patients With Cardiovascular Disease: A Meta …

CR Wei, F Lakhdhir, A Rawat, AK Isaak, A Riaz… - Cureus, 2023 - ncbi.nlm.nih.gov
The aim of this study was to assess and compare the efficacy of atorvastatin with
rosuvastatin in preventing cardiovascular events among patients already diagnosed with …

[HTML][HTML] Clinical-and cost-effectiveness of LDL particle-guided statin therapy: a simulation study

HJ Folse, D Goswami, B Rengarajan, M Budoff, R Kahn - Atherosclerosis, 2014 - Elsevier
Abstract We used the Archimedes Model, a mathematical simulation model (Model) to
estimate the clinical-and cost-effectiveness of using LDL particle concentration (LDL-P) as …

Effect of statin therapy patterns on readmission and mortality in patients with intracerebral hemorrhage

R Yang, J Wu, H Yu, S Wang, H Chen, M Wang… - Journal of Thrombosis …, 2024 - Springer
There is limited and inconsistent evidence for the association of statin therapy and statin
treatment patterns with the risk of recurrent intracerebral hemorrhage (ICH) in patients with …

Clinical trial simulation methods for estimating the impact of DPP-4 inhibitors on cardiovascular disease

CA Schuetz, SH Ong, M Blüher - ClinicoEconomics and Outcomes …, 2015 - Taylor & Francis
Introduction Dipeptidyl peptidase-4 (DPP-4) inhibitors are a class of oral antidiabetic agents
for the treatment of type 2 diabetes mellitus, which lower blood glucose without causing …