Antibiotics have revolutionized medicine, saving countless lives since their discovery in the
early 20th century. However, the origin of antibiotics is now overshadowed by the alarming …

Accumulating evidence suggests that the response of bacteria to antibiotics is significantly
affected by the presence of other interacting microbes. These interactions are not typically …

Antimicrobial resistance (AMR) is a major global public health concern, shared by a large
number of human and animal health actors. Within the framework of a One Health approach …

Biofilm-associated bacteria are less sensitive to antibiotics than free-living (planktonic) cells.
Furthermore, with variations in the concentration of antibiotics throughout a biofilm, microbial …

Staphylococci, like Staphylococcus aureus and S. epidermidis, are common colonizers of
the human microbiota. While being harmless in many cases, many virulence factors result in …

Highlights•Combinations of antibiotics lead to synergistic and antagonistic drug
interactions.•The underlying mechanisms of drug interactions can be elucidated using novel …

For decades, coastal marine ecosystems have been threatened by a wide range of
anthropogenic pollutants. Recently, there has been increasing concern about the …

Broad‐spectrum antibiotics target multiple gram‐positive and gram‐negative bacteria, and
can collaterally damage the gut microbiota. Yet, our knowledge of the extent of damage, the …

Bacterial drug resistance is rapidly developing as one of the greatest threats to human
health. Bacteria will adopt corresponding strategies to crack the inhibitory effect of antibiotics …

Control interventions steer the evolution of molecules, viruses, microorganisms or other cells
towards a desired outcome. Applications range from engineering biomolecules and …