Neuron modeling may be said to have originated with the Hodgkin and Huxley action
potential model in 1952 and Rall's models of integrative activity of dendrites in 1964. Over …

Essentially all cortical areas receive thalamic inputs and send outputs to lower motor
centers. Cortical areas communicate with each other by means of direct corticocortical and …

Primates interact with the world by exploring visual objects; they seek opportunities to view
novel objects even when these have no extrinsic reward value. How the brain controls this …

The primary somatosensory barrel cortex processes tactile vibrissae information, allowing
rodents to actively perceive spatial and textural features of their immediate surroundings …

The thalamus is the major source of cortical inputs shaping sensation, action, and cognition.
Thalamic circuits are targeted by two major inhibitory systems: the thalamic reticular nucleus …

The rodent whisker system is widely used as a model system for investigating sensorimotor
integration, neural mechanisms of complex cognitive tasks, neural development, and …

Thalamic oscillators contribute to both normal rhythms associated with sleep and anesthesia
and abnormal, hypersynchronous oscillations that manifest behaviorally as absence …

Corticothalamic pathways, responsible for the top-down control of the thalamus, have a
canonical organization such that every cortical region sends output from both layer 6 (L6) …

A key question in systems neuroscience is to identify how sensory stimuli are represented in
neuronal activity, and how the activity of sensory neurons in turn is “read out” by downstream …

Prethalamic nuclei in the mammalian brain include the zona incerta, the ventral lateral
geniculate nucleus, and the intergeniculate leaflet, which provide long-range inhibition to …