Feeling force: physical and physiological principles enabling sensory mechanotransduction
S Katta, M Krieg, MB Goodman - Annual review of cell and …, 2015 - annualreviews.org
Organisms as diverse as microbes, roundworms, insects, and mammals detect and respond
to applied force. In animals, this ability depends on ionotropic force receptors, known as …
to applied force. In animals, this ability depends on ionotropic force receptors, known as …
[HTML][HTML] Mechanotransduction in mammalian sensory hair cells
GA Caprara, AW Peng - Molecular and Cellular Neuroscience, 2022 - Elsevier
In the inner ear, the auditory and vestibular systems detect and translate sensory information
regarding sound and balance. The sensory cells that transform mechanical input into an …
regarding sound and balance. The sensory cells that transform mechanical input into an …
Structures of the TMC-1 complex illuminate mechanosensory transduction
H Jeong, S Clark, A Goehring… - Nature, 2022 - nature.com
The initial step in the sensory transduction pathway underpinning hearing and balance in
mammals involves the conversion of force into the gating of a mechanosensory transduction …
mammals involves the conversion of force into the gating of a mechanosensory transduction …
Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5
Hearing and balance involve the transduction of mechanical stimuli into electrical signals by
deflection of bundles of stereocilia linked together by protocadherin 15 (PCDH15) and …
deflection of bundles of stereocilia linked together by protocadherin 15 (PCDH15) and …
Beyond cell–cell adhesion: sensational cadherins for hearing and balance
A Jaiganesh, Y Narui… - Cold Spring …, 2018 - cshperspectives.cshlp.org
Cadherins form a large family of proteins often involved in calcium-dependent cellular
adhesion. Although classical members of the family can provide a physical bond between …
adhesion. Although classical members of the family can provide a physical bond between …
Transduction and encoding sensory information by skin mechanoreceptors
Physical contact with the external world occurs through specialized neural structures called
mechanoreceptors. Cutaneous mechanoreceptors provide information to the central …
mechanoreceptors. Cutaneous mechanoreceptors provide information to the central …
Sensor devices inspired by the five senses: a review
MI Svechtarova, I Buzzacchera, BJ Toebes… - …, 2016 - Wiley Online Library
Wearable devices (wearables) have recently gained significant traction and are predicted to
dominate many areas of research over the next 5 years. Many wearables contain a host of …
dominate many areas of research over the next 5 years. Many wearables contain a host of …
In situ motions of individual inner-hair-cell stereocilia from stapes stimulation in adult mice
In vertebrate hearing organs, mechanical vibrations are converted to ionic currents through
mechanoelectrical-transduction (MET) channels. Concerted stereocilia motion produces an …
mechanoelectrical-transduction (MET) channels. Concerted stereocilia motion produces an …
The biophysics of piezo1 and piezo2 mechanosensitive channels
The ability to sense mechanical stimuli and elaborate a response to them is a fundamental
process in all organisms, driving crucial mechanisms ranging from cell volume regulation up …
process in all organisms, driving crucial mechanisms ranging from cell volume regulation up …
Development and localization of reverse-polarity mechanotransducer channels in cochlear hair cells
M Beurg, AC Goldring, AJ Ricci… - Proceedings of the …, 2016 - National Acad Sciences
Cochlear hair cells normally detect positive deflections of their hair bundles, rotating toward
their tallest edge, which opens mechanotransducer (MT) channels by increased tension in …
their tallest edge, which opens mechanotransducer (MT) channels by increased tension in …