The emerging complexity of the transcriptional landscape poses great challenges to our
conventional preconceptions of how the genome regulates brain function and dysfunction …

miR-132 is an endogenous small RNA and controls post-transcriptional regulation of gene
expression via controlled degradation of mRNA or transcription inhibition. In the nervous …

Neural stem cells residing in the hippocampal neurogenic niche sustain lifelong
neurogenesis in the adult brain. Adult hippocampal neurogenesis (AHN) is functionally …

Vascular integrity helps maintain brain microenvironment homeostasis, which is critical for
the normal development and function of the central nervous system. It is known that neural …

Abstract microRNA‐132 (miR‐132) is involved in prosurvival, anti‐inflammatory and memory‐
promoting functions in the nervous system and has been found consistently downregulated …

Summary microRNA-132 (miR-132), a known neuronal regulator, is one of the most robustly
downregulated microRNAs (miRNAs) in the brain of Alzheimer's disease (AD) patients …

The abnormal regulation of amyloid-β (Aβ) metabolism (eg, production, cleavage,
clearance) plays a central role in Alzheimer's disease (AD). Among endogenous factors …

With the consideration of the broad involvement of microRNAs (miRNAs) in the regulation of
molecular networks in the brain, it is not surprising that miRNA dysregulation causes …

Background/Aims: microRNAs are of vital importance in neural development. As a brain-
specific miRNA, miR-132 has been well studied in mature neurons. However, its role in …

Personalized and regenerative medicine is an emerging therapeutic strategy that is based
on cell biology and biomedical engineering used to develop biological substitutes to …