Systemic sclerosis, also known as scleroderma, is a rare and complex autoimmune
connective-tissue disease. Once considered an untreatable and unpredictable condition …

Chimeric antigen receptor (CAR) T cells are highly effective at targeting and eliminating cells
of the B cell lineage. CAR T cell therapy has become a standard-of-care treatment for …

Brain diseases, such as brain tumors, neurodegenerative diseases, cerebrovascular
diseases, and brain injuries, are caused by various pathophysiological changes, which pose …

Abstract Background Systemic sclerosis (SSc) is a systemic autoimmune disease with
heterogeneous clinical presentation and prognosis. JAK inhibitors reduced cutaneous and …

Diffuse cutaneous systemic sclerosis (dcSSc) is associated with high mortality resulting from
early internal-organ involvement. Clinicians therefore tend to focus on early diagnosis and …

Systemic sclerosis and autoimmune myositis are both associated with decreased quality of
life and increased mortality. Their prognosis and management largely depend on the …

Primary systemic sclerosis heart involvement (pSHI) is an important disease manifestation
that accounts for a significant proportion of systemic sclerosis (SSc)-associated mortality. A …

Systemic Sclerosis (SSc) is an autoimmune disease marked by dysregulation of the immune
system, tissue fibrosis and dysfunction of the vasculature. Vascular damage, remodeling and …

Background Early diffuse cutaneous systemic sclerosis (dcSSc) has the highest case fatality
among rheumatic diseases. We report baseline characteristics, current immunosuppressive …

Objectives To compare current all-cause mortality rates in rheumatoid arthritis (RA),
ankylosing spondylitis (AS), psoriatic arthritis (PsA), systemic lupus erythematosus (SLE) …