We conducted a systematic literature review to identify and critically evaluate studies of
serious adverse health effects (SAHEs) in humans using nicotine replacement therapy …

This review gives a brief overview over the major aspects of application of the nicotine
alkaloid and its close derivatives in the therapy of some neurodegenerative disorders and …

Introduction: New approaches to electronic cigarettes (e-cigarettes) as a form of nicotine
replacement therapy (NRT) may reduce the rates of tobacco-related disease and mortality …

Introduction: The vast majority of work on the physiological effects of nicotine in humans has
been done in smokers or smokers trying to quit. Such studies can be confounded by …

An aversive tobacco abstinence syndrome, thought to reflect an underlying level of nicotine
dependence, contributes to cigarette smokers' failed quit attempts. Nicotine replacement …

This paper presents personal reflections on the history, current status and the future of
research on smoking relapse. Relapse was traditionally viewed primarily as an outcome, to …

Cigarette smoke contains nicotine, an immunomodulatory component that is thought to affect
immune surveillance and increase the progression of diseases. Dendritic cells (DCs) …

The aim of this study was to prepare a drug-in-adhesive patch of nicotine (NIC) and use ion-
pair strategy to regulate drug delivery rate. Moreover, the mechanism of how ion-pair …

Nicotine replacement therapy (NRT) has been used in the treatment of tobacco dependence
for over three decades. Whilst the choice of NRT was limited early on, in the last ten years …

Cigarette smoking is a major public health problem that causes more than 5 million deaths
annually worldwide. Cigarette smoking is especially common among individuals with …