Three-way junction skeleton biosensors based on aptamers, DNAzymes, and DNA hybridization probes
Nucleic acids can be used as building blocks for highly regular and complex structures at
the nanoscale due to their inherent self-assembly and programmability resulting from intra …
the nanoscale due to their inherent self-assembly and programmability resulting from intra …
A modular aldol approach for internal fluorescent molecular rotor chalcone surrogates for DNA biosensing applications
RE Johnson, MT Murray, LJ Bycraft, SD Wetmore… - Chemical …, 2023 - pubs.rsc.org
Fluorescent molecular rotors (FMRs) are critical tools for probing nucleic acid structure and
function. Many valuable FMRs have been incorporated into oligonucleotides, although the …
function. Many valuable FMRs have been incorporated into oligonucleotides, although the …
Redox Reporter‐Ligand Competition to Support Signaling in the Cocaine‐Binding Electrochemical Aptamer‐Based Biosensor
P Dauphin‐Ducharme, ZR Churcher… - … A European Journal, 2023 - Wiley Online Library
Electrochemical aptamer‐based (E‐AB) biosensors have demonstrated capabilities in
monitoring molecules directly in undiluted complex matrices and in the body with the hopes …
monitoring molecules directly in undiluted complex matrices and in the body with the hopes …
Solution and Gas-Phase Stability of DNA Junctions from Temperature-Controlled Electrospray Ionization and Surface-Induced Dissociation
A Pruška, JA Harrison, A Granzhan… - Analytical …, 2023 - ACS Publications
DNA three-way junction (TWJ) structures transiently form during key cellular processes such
as transcription, replication, and DNA repair. Despite their significance, the thermodynamics …
as transcription, replication, and DNA repair. Despite their significance, the thermodynamics …
DNA binding by the antimalarial compound artemisinin
Artemisinin (ART) is a vital medicinal compound that is used alone or as part of a
combination therapy against malaria. ART is thought to function by attaching to heme …
combination therapy against malaria. ART is thought to function by attaching to heme …
An ultrasensitive liquid crystal aptasensing chip assisted by three-way junction DNA pockets for acrylamide detection in food samples
Acrylamide, an unsaturated amide found in heat-processed foods, poses serious risks to
human health due to its neurotoxicity, carcinogenicity, and genotoxicity. This highlights the …
human health due to its neurotoxicity, carcinogenicity, and genotoxicity. This highlights the …
Thieno[3,2-b]thiophene for the Construction of Far-Red Molecular Rotor Hemicyanines as High-Affinity DNA Aptamer Fluorogenic Reporters
The construction of far-red fluorescent molecular rotors (FMRs) is an imperative task for
developing nucleic acid stains that have superior compatibility with cellular systems and …
developing nucleic acid stains that have superior compatibility with cellular systems and …
Tuning the DNA binding properties of phenolic hemicyanine dyes for host-guest fluorescent aptasensor applications
AJ Van Riesen, B Kalnitsky, AA Shoara, S Slavkovic… - Dyes and …, 2023 - Elsevier
Fluorescent dyes that bind specifically to DNA aptamers with turn-on emission serve as
powerful tools for biosensor development. DNA three-way junctions (3WJs) consisting of a Y …
powerful tools for biosensor development. DNA three-way junctions (3WJs) consisting of a Y …
Fluorogenic target competitors for developing label-free and sensitive folding-unswitching aptamer sensors
X Zeng, X Tong, J Chen, Q Chen, R Lai, Q Xu… - Analytica Chimica …, 2024 - Elsevier
Background Aptamers have aroused tremendous applications in sensors, drug deliveries,
diagnosis, and therapies. In particular, target-induced global structure switching of aptamers …
diagnosis, and therapies. In particular, target-induced global structure switching of aptamers …
Amodiaquine Nonspecifically Binds Double Stranded and Three‐Way Junction DNA Structures
S Slavkovic, AA Shoara, YA Kaiyum… - …, 2024 - Wiley Online Library
The 4‐aminoquinoline class of compounds includes the important antimalarial compounds
amodiaquine and chloroquine. Despite their medicinal importance, the mode of action of …
amodiaquine and chloroquine. Despite their medicinal importance, the mode of action of …