This paper reviews the recent developments in the field of biomedical optical imaging,
emphasizing technologies that have been moved from'bench top to bedside'. Important new …

Cervical cancer is one of the most common and lethal gynecological malignancies in both
developing and developed countries, and therefore, there is a considerable interest in early …

The purpose of this study was to determine whether in vivo images of oral mucosa obtained
with a fiber optic confocal reflectance microscope could be used to differentiate normal and …

Cervical cancer is the second most common female cancer worldwide. The ability to quantify
physiological and morphological changes in the cervix is not only useful in the diagnosis of …

Please cite this paper as: Louwers J, Zaal A, Kocken M, ter Harmsel W, Graziosi G, Spruijt J,
Berkhof J, Balas C, Papagiannakis E, Snijders P, Meijer C, van Kemenade F, Verheijen R …

Immature and dysplastic cervical squamous epithelium whitens after the application of acetic
acid during a colposcopic examination. The whitening process occurs visually over several …

Recent clinical studies on human skin indicated that in vivo multi-harmonic generation
microscopy (HGM) can achieve sub-micron resolution for histopathological analysis with a …

Purpose: Colposcopy occupies a key role in the prevention of cervical cancer by identifying
preinvasive or invasive lesions. However, colposcopy is subjective and is responsible for …

Cervical intraepithelial neoplasia (CIN) exhibits certain morphologic features that can be
identified during a colposcopic exam. Immature metaplastic and dysplastic cervical …

We present a single fiber reflectance confocal microscope with a two dimensional MEMS
gimbaled scanner. Achieved lateral and axial resolutions are 0.82 μm and 13 μm …