Cutaneous wound healing: An update from physiopathology to current therapies

LFS Gushiken, FP Beserra, JK Bastos, CJ Jackson… - Life, 2021 - mdpi.com
The skin is the biggest organ of human body which acts as a protective barrier against
deleterious agents. When this barrier is damaged, the organism promotes the healing …

2D and 3D electrospinning technologies for the fabrication of nanofibrous scaffolds for skin tissue engineering: A review

A Keirouz, M Chung, J Kwon… - Wiley …, 2020 - Wiley Online Library
This review provides insights into the current advancements in the field of electrospinning,
focusing on its applications for skin tissue engineering. Furthermore, it reports the …

Silk fibroin biomaterials and their beneficial role in skin wound healing

Ł Mazurek, M Szudzik, M Rybka, M Konop - Biomolecules, 2022 - mdpi.com
The skin, acting as the outer protection of the human body, is most vulnerable to injury.
Wound healing can often be impaired, leading to chronic, hard-to-heal wounds. For this …

The current status of mesenchymal stromal cells: controversies, unresolved issues and some promising solutions to improve their therapeutic efficacy

D García-Bernal, M García-Arranz… - Frontiers in Cell and …, 2021 - frontiersin.org
Mesenchymal stromal cells (MSCs) currently constitute the most frequently used cell type in
advanced therapies with different purposes, most of which are related with inflammatory …

Cellular human tissue-engineered skin substitutes investigated for deep and difficult to heal injuries

Á Sierra-Sánchez, KH Kim, G Blasco-Morente… - NPJ Regenerative …, 2021 - nature.com
Wound healing is an important function of skin; however, after significant skin injury (burns)
or in certain dermatological pathologies (chronic wounds), this important process can be …

[HTML][HTML] Advances in spray products for skin regeneration

P Pleguezuelos-Beltrán, P Gálvez-Martín… - Bioactive materials, 2022 - Elsevier
To date, skin wounds are still an issue for healthcare professionals. Although numerous
approaches have been developed over the years for skin regeneration, recent advances in …

Electrospinning nanofibers to 1D, 2D, and 3D scaffolds and their biomedical applications

H Zhong, J Huang, J Wu, J Du - Nano Research, 2022 - Springer
Electrospinning is a popular and effective method of producing porous nanofibers with a
large surface area, superior physical and chemical properties, and a controllable pore size …

Silk fibroin-based therapeutics for impaired wound healing

T Lehmann, AE Vaughn, S Seal, KW Liechty, C Zgheib - Pharmaceutics, 2022 - mdpi.com
Impaired wound healing can lead to local hypoxia or tissue necrosis and ultimately result in
amputation or even death. Various factors can influence the wound healing environment …

Vascularization strategies for skin tissue engineering

A Amirsadeghi, A Jafari, LJ Eggermont… - Biomaterials …, 2020 - pubs.rsc.org
A number of challenges in skin grafting for wound healing have drawn researchers to focus
on skin tissue engineering as an alternative solution. The core idea of tissue engineering is …

Microskin‐Inspired Injectable MSC‐Laden Hydrogels for Scarless Wound Healing with Hair Follicles

X Zheng, Z Ding, W Cheng, Q Lu… - Advanced …, 2020 - Wiley Online Library
Scarless skin regeneration with functional tissue remains a challenge for full‐thickness
wounds. Here, mesenchymal stem cell (MSC)‐laden hydrogels are developed for scarless …