COVID‐19 immunopathology with emphasis on Th17 response and cell‐based immunomodulation therapy: potential targets and challenges
A Pourgholaminejad… - Scandinavian Journal …, 2022 - Wiley Online Library
The role of the immune system against coronavirus disease 2019 (COVID‐19) is unknown in
many aspects, and the protective or pathologic mechanisms of the immune response are …
many aspects, and the protective or pathologic mechanisms of the immune response are …
Role of inflammatory factors in the etiology and treatment of recurrent implantation failure
Q Wang, Y Sun, R Fan, M Wang, C Ren, A Jiang… - Reproductive …, 2022 - Elsevier
Recurrent implantation failure (RIF) is characterized by the absence of implantation after
high-grade embryos are transferred to the endometrium by at least three in vitro fertilization …
high-grade embryos are transferred to the endometrium by at least three in vitro fertilization …
Protection by hydroxychloroquine prevents placental injury in obstetric antiphospholipid syndrome
J Liu, L Zhang, Y Tian, S Wan, M Hu… - Journal of Cellular …, 2022 - Wiley Online Library
Obstetric antiphospholipid syndrome (OAPS) is mediated by antiphospholipid antibodies
(aPLs, and anti‐β2 glycoprotein I antibody is the main pathogenic antibody), and recurrent …
(aPLs, and anti‐β2 glycoprotein I antibody is the main pathogenic antibody), and recurrent …
Molecular insights into the MAPK cascade during viral infection: potential crosstalk between HCQ and HCQ analogues
The mitogen‐activated protein kinase (MAPK) pathway links the cell‐surface receptors to the
transcription machinery, transducing the extracellular signals into several outputs, which …
transcription machinery, transducing the extracellular signals into several outputs, which …
Hydroxychloroquine induces oxidative DNA damage and mutation in mammalian cells
Since the early stages of the pandemic, hydroxychloroquine (HCQ), a widely used drug with
good safety profile in clinic, has come to the forefront of research on drug repurposing for …
good safety profile in clinic, has come to the forefront of research on drug repurposing for …
[HTML][HTML] Modulating the controlled release of hydroxychloroquine mobilized on pectin films through film-forming pH and incorporation of nanocellulose
GC Zambuzi, CHM Camargos, MP Ferreira… - Carbohydrate polymer …, 2021 - Elsevier
Materials from renewable resources like pectin and nanocelluloses are useful for the
controlled release of drugs such as hydroxychloroquine (HCQ), whose potential for treating …
controlled release of drugs such as hydroxychloroquine (HCQ), whose potential for treating …
Multi-compartment lymph-node-on-a-chip enables measurement of immune cell motility in response to drugs
Organs On-a-Chip represent novel platforms for modelling human physiology and disease.
The lymph node (LN) is a relevant immune organ in which B and T lymphocytes are spatially …
The lymph node (LN) is a relevant immune organ in which B and T lymphocytes are spatially …
Association between interferon-I producing plasmacytoid dendritic cells and thrombotic antiphospholipid syndrome
AP Rosa dos Santos, C de Oliveira Vaz… - Lupus, 2022 - journals.sagepub.com
Background: Thrombotic risk in antiphospholipid syndrome (APS) is conferred by the
association of antiphospholipid (aPL) antibodies (first hit) with additional pro-coagulant …
association of antiphospholipid (aPL) antibodies (first hit) with additional pro-coagulant …
The presumable effects of hydroxychloroquine and its metabolites in the treatment of systemic lupus erythematosus
M Pan, R Jin, Y Dai, B Gao, Y Liu, X Peng… - International …, 2024 - Elsevier
Objective Hydroxychloroquine (HCQ) is an essential drug in the treatment of systemic lupus
erythematosus (SLE). This study aimed to detect the concentrations of HCQ and its …
erythematosus (SLE). This study aimed to detect the concentrations of HCQ and its …
Construction of Chiral Cyclobutanone-Fused 4-Aminoquinolines via Sequential Chiral Phosphoric Acid and Palladium Catalysis
S Zhang, RS Jin, YF Niu, XP Zeng - The Journal of Organic …, 2023 - ACS Publications
A one-pot catalytic asymmetric route to novel chiral quaternary-carbon-containing
cyclobutanone-fused 4-aminoquinoline derivatives in good to high yields and …
cyclobutanone-fused 4-aminoquinoline derivatives in good to high yields and …