[HTML][HTML] Metabolomics in Pulmonary Hypertension—A Useful Tool to Provide Insights into the Dark Side of a Tricky Pathology
PP Bassareo, M D'Alto - International Journal of Molecular Sciences, 2023 - mdpi.com
Pulmonary hypertension (PH) is a multifaceted illness causing clinical manifestations like
dyspnea, fatigue, and cyanosis. If left untreated, it often evolves into irreversible pulmonary …
dyspnea, fatigue, and cyanosis. If left untreated, it often evolves into irreversible pulmonary …
Application of Metabolomics across the Spectrum of Pulmonary and Critical Care Medicine
CE Simpson, JG Ledford, G Liu - American journal of respiratory cell …, 2024 - atsjournals.org
In recent years, metabolomics, the systematic study of small-molecule metabolites in
biological samples, has yielded fresh insights into the molecular determinants of pulmonary …
biological samples, has yielded fresh insights into the molecular determinants of pulmonary …
Spatial and temporal resolution of metabolic dysregulation in the Sugen hypoxia model of pulmonary hypertension
Although PAH is partially attributed to disordered metabolism, previous human studies have
mostly examined circulating metabolites at a single time point, potentially overlooking crucial …
mostly examined circulating metabolites at a single time point, potentially overlooking crucial …
Fatty acid metabolism promotes TRPV4 activity in lung microvascular endothelial cells in pulmonary arterial hypertension
Pulmonary arterial hypertension (PAH) is a morbid disease characterized by significant lung
endothelial cell (EC) dysfunction. Prior work has shown that microvascular endothelial cells …
endothelial cell (EC) dysfunction. Prior work has shown that microvascular endothelial cells …
[HTML][HTML] Use of Raman spectroscopy to study rat lung tissues for distinguishing asphyxia from sudden cardiac death
K Zhang, R Liu, X Wei, Z Wang, P Huang - RSC advances, 2024 - pubs.rsc.org
Determining asphyxia as the cause of death is crucial but is based on an exclusive strategy
because it lacks sensitive and specific morphological characteristics in forensic practice. In …
because it lacks sensitive and specific morphological characteristics in forensic practice. In …
A multimodal approach identifies lactate as a central feature of right ventricular failure that is detectable in human plasma
A Hemnes, N Fortune, K Simon, IA Trenary… - Frontiers in …, 2024 - frontiersin.org
Background In PAH metabolic abnormalities in multiple pathways are well-recognized
features of right ventricular dysfunction, however, prior work has focused mainly on the use …
features of right ventricular dysfunction, however, prior work has focused mainly on the use …
[引用][C] Metabolomics of pulmonary hypertension: from pathological mechanisms to therapeutic targets
Y DENG, X WANG - Basic & Clinical Medicine, 2024