Natural history of mesenchymal stem cells, from vessel walls to culture vessels

IR Murray, CC West, WR Hardy, AW James… - Cellular and Molecular …, 2014 - Springer
Mesenchymal stem/stromal cells (MSCs) can regenerate tissues by direct differentiation or
indirectly by stimulating angiogenesis, limiting inflammation, and recruiting tissue-specific …

Cell-based therapies for experimental chronic kidney disease: a systematic review and meta-analysis

DA Papazova, NR Oosterhuis… - Disease models & …, 2015 - journals.biologists.com
Cell-based therapy is a promising strategy for treating chronic kidney disease (CKD) and is
currently the focus of preclinical studies. We performed a systematic review and meta …

Mesenchymal stem cells protect podocytes from apoptosis induced by high glucose via secretion of epithelial growth factor

D Li, N Wang, L Zhang, Z Hanyu, B Xueyuan… - Stem cell research & …, 2013 - Springer
Introduction The apoptosis and subsequent injury of podocytes plays a pathogenic role in
diabetic nephropathy (DN). Mesenchymal stem cells (MSCs) are promising therapeutic cells …

CXCR4 antagonism as a therapeutic approach to prevent acute kidney injury

A Zuk, M Gershenovich, Y Ivanova… - American Journal …, 2014 - journals.physiology.org
We examined whether antagonism of the CXCR4 receptor ameliorates the loss of renal
function following ischemia-reperfusion. CXCR4 is ubiquitously expressed on leukocytes …

Mesenchymal stem cell-based therapies against podocyte damage in diabetic nephropathy

M Khalilpourfarshbafi, F Hajiaghaalipour… - Tissue Engineering and …, 2017 - Springer
Injury to podocytes is an early event in diabetic nephropathy leading to proteinuria with
possible progression to end-stage renal failure. The podocytes are unique and highly …

[HTML][HTML] Hematopoietic stem cells derived from human umbilical cord ameliorate cisplatin-induced acute renal failure in rats

RH Shalaby, LA Rashed, AE Ismaail… - American journal of …, 2014 - ncbi.nlm.nih.gov
Injury to a target organ can be sensed by bone marrow stem cells that migrate to the site of
damage, undergo differentiation, and promote structural and functional repair. This …

Stem cells: potential and challenges for kidney repair

M Herrera, M Mirotsou - American Journal of Physiology …, 2014 - journals.physiology.org
Renal damage resulting from acute and chronic kidney injury poses an important problem to
public health. Currently, patients with end-stage renal disease rely solely on kidney …

Cell projections and extracellular matrix cross the interstitial interface within the renal stem/progenitor cell niche: accidental, structural or functional cues?

WW Minuth, L Denk - Nephron Experimental Nephrology, 2012 - karger.com
Background: During nephron induction, morphogenetic molecules are reciprocally
exchanged between epithelial and mesenchymal stem/progenitor cells within the renal …

MR tracking of SPIO‐labeled mesenchymal stem cells in rats with liver fibrosis could not monitor the cells accurately

B Zhou, D Li, J Qian, Z Li, P Pang… - Contrast media & …, 2015 - Wiley Online Library
Our previous study showed that in vivo magnetic resonance (MR) imaging is effective in
tracking superparamagnetic iron oxide (SPIO)‐labeled bone marrow mesenchymal stem …

Structural links between the renal stem/progenitor cell niche and the organ capsule

WW Minuth, L Denk - Histochemistry and cell biology, 2014 - Springer
A special feature of the renal stem/progenitor cell niche is its always close neighborhood to
the capsule during organ development. To explore this link, neonatal kidney was …