The development of a vaccine for Fasciola spp. in livestock is a challenge and would be
advanced by harnessing our knowledge of acquired immune mechanisms expressed by …

Trematode parasites live in the liver, fore stomachs or blood vessels of a wide range of
animals and humans. Most of them have a special economic and veterinary significance …

Many parasitic helminthes of veterinary importance have genetic features that favor
development of anthelmintic resistance, this becoming a major worldwide constrain in …

Infection of ruminants by Fasciola spp continues to cause large economic losses worldwide.
Recent results from several laboratories have demonstrated that animals can be significantly …

The surface tegument of the liver fluke Fasciola hepatica is a syncytial cytoplasmic layer
bounded externally by a plasma membrane and covered by a glycocalyx, which constitutes …

As a direct consequence of rising drug resistance among common nematodes of grazing
animals, efforts toward state-of-the-art vaccine development have clearly intensified in …

Abstract Background Glutathione-S-transferase (GST) is a widespread multigene family of
detoxification enzymes. The vaccination of mice with recombinant GST of 24 kDa from …

Defined molecular vaccines for several ruminant helminth parasites are being pursued at
several different laboratories. The most fruitful sources of antigen have been oncosphere …

Background Lymphatic filarial parasites survive within the lymphatic vessels for years
despite the complex immune environment surrounding them. Parasites possibly accomplish …

Vaccine trials were conducted in Brahman cross cattle evaluating the efficacy of 4 native
antigens purified from adult Fasciola gigantica flukes, and 1 recombinant F. gigantica …